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2012


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Deformation-driven formation of equilibrium phases in the Cu-Ni alloys

Straumal, B. B., Protasova, S. G., Mazilkin, A. A., Rabkin, E., Goll, D., Schütz, G., Baretzky, B., Valiev, R. Z.

{Journal of Materials Science}, 47, pages: 360-367, 2012 (article)

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DOI [BibTex]

2012


DOI [BibTex]


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Nanosponges for hydrogen storage

Schlichtenmayer, M., Hirscher, M.

{Journal of Materials Chemistry}, 22, pages: 10134-10143, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Magnetic and electronic properties of the interface between half metallic Fe3O4 and semiconducting ZnO

Brück, S., Paul, M., Tian, H., Müller, A., Kufer, D., Praetorius, C., Fauth, K., Audehm, P., Goering, E., Verbeeck, J., Van Tendeloo, G., Sing, M., Claessen, R.

{Applied Physics Letters}, 100, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Amorphous interlayers between crystalline grains in ferromagnetic ZnO films

Straumal, B. B., Protasova, S. G., Mazilkin, A. A., Baretzky, B., Myatiev, A. A., Straumal, P. B., Tietze, T., Schütz, G., Goering, E.

{Materials Letters}, 71, pages: 21-24, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Model-free reinforcement learning of impedance control in stochastic environments

Stulp, Freek, Buchli, Jonas, Ellmer, Alice, Mistry, Michael, Theodorou, Evangelos A., Schaal, S.

Autonomous Mental Development, IEEE Transactions on, 4(4):330-341, 2012 (article)

am

[BibTex]

[BibTex]


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Shape-Programmable Soft Capsule Robots for Semi-Implantable Drug Delivery

Yim, S., Sitti, M.

Mechatronics, IEEE/ASME Transactions on, 2012 (article)

pi

Project Page [BibTex]

Project Page [BibTex]


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Control of multiple heterogeneous magnetic microrobots in two dimensions on nonspecialized surfaces

Diller, E., Floyd, S., Pawashe, C., Sitti, M.

IEEE Transactions on Robotics, 28(1):172-182, IEEE, 2012 (article)

pi

[BibTex]

[BibTex]


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Gecko-Inspired Controllable Adhesive Structures Applied to Micromanipulation

Mengüç, Y., Yang, S. Y., Kim, S., Rogers, J. A., Sitti, M.

Advanced Functional Materials, 22(6):1245-1245, WILEY-VCH Verlag, 2012 (article)

pi

Project Page [BibTex]

Project Page [BibTex]


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Elastomer surfaces with directionally dependent adhesion strength and their use in transfer printing with continuous roll-to-roll applications

Yang, S. Y., Carlson, A., Cheng, H., Yu, Q., Ahmed, N., Wu, J., Kim, S., Sitti, M., Ferreira, P. M., Huang, Y., others,

Advanced Materials, 24(16):2117-2122, WILEY-VCH Verlag, 2012 (article)

pi

[BibTex]

[BibTex]


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Effect of retraction speed on adhesion of elastomer fibrillar structures

Abusomwan, U., Sitti, M.

Applied Physics Letters, 101(21):211907, AIP, 2012 (article)

pi

Project Page [BibTex]

Project Page [BibTex]


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Burn-in, bias, and the rationality of anchoring

Lieder, F., Griffiths, T. L., Goodman, N. D.

Advances in Neural Information Processing Systems 25, pages: 2699-2707, 2012 (article)

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[BibTex]

[BibTex]


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Accelerated diffusion and phase transformations in Co-Cu alloys driven by the severe plastic deformation

Straumal, B. B., Mazilkin, A. A., Baretzky, B., Schütz, G., Rabkin, E., Valiev, R. Z.

{Special Issue on Advanced Materials Science in Bulk Nanostructured Metals}, 53(1):63-71, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Unusual flux jumps above 12 K in non-homogeneous MgB2 thin films

Treiber, S., Stahl, C., Schütz, G., Albrecht, J.

{Superconductor Science \& Technology}, 25, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Ferromagnetism of nanostructured zinc oxide films

Straumal, B. B., Mazilkin, A. A., Protasova, S. G., Straumal, P. B., Myatiev, A. A., Schütz, G., Goering, E., Baretzky, B.

{The Physics of Metals and Metallography}, 113(13):1244-1256, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Frequencies and polarization vectors of phonons: Results from force constants which are fitted to experimental data or calculated ab initio

Illg, C., Meyer, B., Fähnle, M.

{Physical Review B}, 86(17), Published by the American Physical Society through the American Institute of Physics, Woodbury, NY, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Grain boundary wetting by a second solid phase in the Zr-Nb alloys

Straumal, B. B., Gornakova, A. S., Kucheev, Y. O., Baretzky, B., Nekrasov, A. N.

{Journal of Materials Engineering and Performance}, 21(5):721-724, 2012 (article)

mms

DOI [BibTex]

DOI [BibTex]


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Grain boundary wetting in the NdFeB-based hard magnetic alloys

Straumal, B. B., Kucheev, Y. O., Yatskovskaya, I. L., Mogilnikova, I. V., Schütz, G., Nekrasov, A. N., Baretzky, B.

{Journal of Materials Science}, 47(24):8352-8359, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


Natural Metrics and Least-Committed Priors for Articulated Tracking
Natural Metrics and Least-Committed Priors for Articulated Tracking

Soren Hauberg, Stefan Sommer, Kim S. Pedersen

Image and Vision Computing, 30(6-7):453-461, Elsevier, 2012 (article)

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Publishers site Code PDF [BibTex]

Publishers site Code PDF [BibTex]


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Reinforcement Learning with Sequences of Motion Primitives for Robust Manipulation

Stulp, F., Theodorou, E., Schaal, S.

IEEE Transactions on Robotics, 2012 (article)

am

[BibTex]

[BibTex]


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Impact and Surface Tension in Water: a Study of Landing Bodies

Shih, B., Laham, L., Lee, K. J., Krasnoff, N., Diller, E., Sitti, M.

Bio-inspired Robotics Final Project, Carnegie Mellon University, 2012 (article)

pi

[BibTex]

[BibTex]


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Design and rolling locomotion of a magnetically actuated soft capsule endoscope

Yim, S., Sitti, M.

IEEE Transactions on Robotics, 28(1):183-194, IEEE, 2012 (article)

pi

Project Page [BibTex]

Project Page [BibTex]


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Design and manufacturing of a controllable miniature flapping wing robotic platform

Arabagi, V., Hines, L., Sitti, M.

The International Journal of Robotics Research, 31(6):785-800, SAGE Publications Sage UK: London, England, 2012 (article)

pi

[BibTex]

[BibTex]


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Chemotactic steering of bacteria propelled microbeads

Kim, D., Liu, A., Diller, E., Sitti, M.

Biomedical microdevices, 14(6):1009-1017, Springer US, 2012 (article)

pi

Project Page [BibTex]

Project Page [BibTex]


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Construct Validity of Instrument Vibrations as a Measure of Robotic Surgical Skill

Gomez, E. D., Bark, K., Rivera, C., McMahan, W., Remington, A., Lee, D. I., Williams, N., Murayama, K., Dumon, K., Kuchenbecker, K. J.

Journal of the American College of Surgeons, 215(3):S119-120, Chicago, Illinois, USA, 2012, Oral presentation given by Gomez at the {\em American College of Surgeons (ACS) Clinical Congress} (article)

hi

[BibTex]

[BibTex]


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Hydrogel microrobots actuated by optically generated vapour bubbles

Hu, W., Ishii, K. S., Fan, Q., Ohta, A. T.

Lab on a Chip, 12(19):3821-3826, Royal Society of Chemistry, 2012 (article)

pi

[BibTex]

[BibTex]


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Magnetic proximity effect in YBa2Cu3O7 / La2/3Ca1/3MnO3 and YBa2Cu3O7 / LaMnO3+δsuperlattices

Satapathy, D. K., Uribe-Laverde, M. A., Marozau, I., Malik, V. K., Das, S., Wagner, T., Marcelot, C., Stahn, J., Brück, S., Rühm, A., Macke, S., Tietze, T., Goering, E., Frañó, A., Kim, J., Wu, M., Benckiser, E., Keimer, B., Devishvili, A., Toperverg, B. P., Merz, M., Nagel, P., Schuppler, S., Bernhard, C.

{Physical Review Letters}, 108, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Noble gases and microporous frameworks; from interaction to application

Soleimani Dorcheh, A., Denysenko, D., Volkmer, D., Donner, W., Hirscher, M.

{Microporous and Mesoporous Materials}, 162, pages: 64-68, Elsevier, Amsterdam, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Note: Unique characterization possibilities in the ultra high vacuum scanning transmission x-ray microscope (UHV-STXM) "MAXYMUS" using a rotatable permanent magnetic field up to 0.22 T

Nolle, D., Weigand, M., Audehm, P., Goering, E., Wiesemann, U., Wolter, C., Nolle, E., Schütz, G.

{Review of Scientific Instruments}, 83(4), 2012 (article)

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DOI [BibTex]


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Microstructure and superconducting properties of MgB2 films prepared by solid state reaction of multilayer precursors of the elements

Kugler, B., Stahl, C., Treiber, S., Soltan, S., Haug, S., Schütz, G., Albrecht, J.

{Thin Solid Films}, 520, pages: 6985-6988, 2012 (article)

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DOI [BibTex]

DOI [BibTex]

2011


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Causal Inference on Discrete Data using Additive Noise Models

Peters, J., Janzing, D., Schölkopf, B.

IEEE Transactions on Pattern Analysis and Machine Intelligence, 33(12):2436-2450, December 2011 (article)

Abstract
Inferring the causal structure of a set of random variables from a finite sample of the joint distribution is an important problem in science. The case of two random variables is particularly challenging since no (conditional) independences can be exploited. Recent methods that are based on additive noise models suggest the following principle: Whenever the joint distribution {\bf P}^{(X,Y)} admits such a model in one direction, e.g., Y=f(X)+N, N \perp\kern-6pt \perp X, but does not admit the reversed model X=g(Y)+\tilde{N}, \tilde{N} \perp\kern-6pt \perp Y, one infers the former direction to be causal (i.e., X\rightarrow Y). Up to now, these approaches only dealt with continuous variables. In many situations, however, the variables of interest are discrete or even have only finitely many states. In this work, we extend the notion of additive noise models to these cases. We prove that it almost never occurs that additive noise models can be fit in both directions. We further propose an efficient algorithm that is able to perform this way of causal inference on finite samples of discrete variables. We show that the algorithm works on both synthetic and real data sets.

ei

PDF Web DOI [BibTex]

2011


PDF Web DOI [BibTex]


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Spontaneous epigenetic variation in the Arabidopsis thaliana methylome

Becker, C., Hagmann, J., Müller, J., Koenig, D., Stegle, O., Borgwardt, K., Weigel, D.

Nature, 480(7376):245-249, December 2011 (article)

Abstract
Heritable epigenetic polymorphisms, such as differential cytosine methylation, can underlie phenotypic variation1, 2. Moreover, wild strains of the plant Arabidopsis thaliana differ in many epialleles3, 4, and these can influence the expression of nearby genes1, 2. However, to understand their role in evolution5, it is imperative to ascertain the emergence rate and stability of epialleles, including those that are not due to structural variation. We have compared genome-wide DNA methylation among 10 A. thaliana lines, derived 30 generations ago from a common ancestor6. Epimutations at individual positions were easily detected, and close to 30,000 cytosines in each strain were differentially methylated. In contrast, larger regions of contiguous methylation were much more stable, and the frequency of changes was in the same low range as that of DNA mutations7. Like individual positions, the same regions were often affected by differential methylation in independent lines, with evidence for recurrent cycles of forward and reverse mutations. Transposable elements and short interfering RNAs have been causally linked to DNA methylation8. In agreement, differentially methylated sites were farther from transposable elements and showed less association with short interfering RNA expression than invariant positions. The biased distribution and frequent reversion of epimutations have important implications for the potential contribution of sequence-independent epialleles to plant evolution.

ei

Web DOI [BibTex]

Web DOI [BibTex]


High-quality reflection separation using polarized images
High-quality reflection separation using polarized images

Kong, N., Tai, Y., Shin, S. Y.

IEEE Transactions on Image Processing, 20(12):3393-3405, IEEE Signal Processing Society, December 2011 (article)

Abstract
In this paper, we deal with a problem of separating the effect of reflection from images captured behind glass. The input consists of multiple polarized images captured from the same view point but with different polarizer angles. The output is the high quality separation of the reflection layer and the background layer from the images. We formulate this problem as a constrained optimization problem and propose a framework that allows us to fully exploit the mutually exclusive image information in our input data. We test our approach on various images and demonstrate that our approach can generate good reflection separation results.

ps

Publisher site [BibTex]

Publisher site [BibTex]


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Human-Inspired Robotic Grasp Control with Tactile Sensing

Romano, J. M., Hsiao, K., Niemeyer, G., Chitta, S., Kuchenbecker, K. J.

IEEE Transactions on Robotics, 27(6):1067-1079, December 2011 (article)

hi

[BibTex]

[BibTex]


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HHfrag: HMM-based fragment detection using HHpred

Kalev, I., Habeck, M.

Bioinformatics, 27(22):3110-3116, November 2011 (article)

Abstract
Motivation: Over the last decade, both static and dynamic fragment libraries for protein structure prediction have been introduced. The former are built from clusters in either sequence or structure space and aim to extract a universal structural alphabet. The latter are tailored for a particular query protein sequence and aim to provide local structural templates that need to be assembled in order to build the full-length structure. Results: Here, we introduce HHfrag, a dynamic HMM-based fragment search method built on the profile–profile comparison tool HHpred. We show that HHfrag provides advantages over existing fragment assignment methods in that it: (i) improves the precision of the fragments at the expense of a minor loss in sequence coverage; (ii) detects fragments of variable length (6–21 amino acid residues); (iii) allows for gapped fragments and (iv) does not assign fragments to regions where there is no clear sequence conservation. We illustrate the usefulness of fragments detected by HHfrag on targets from most recent CASP.

ei

Web DOI [BibTex]

Web DOI [BibTex]


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Reward-Weighted Regression with Sample Reuse for Direct Policy Search in Reinforcement Learning

Hachiya, H., Peters, J., Sugiyama, M.

Neural Computation, 23(11):2798-2832, November 2011 (article)

Abstract
Direct policy search is a promising reinforcement learning framework, in particular for controlling continuous, high-dimensional systems. Policy search often requires a large number of samples for obtaining a stable policy update estimator, and this is prohibitive when the sampling cost is expensive. In this letter, we extend an expectation-maximization-based policy search method so that previously collected samples can be efficiently reused. The usefulness of the proposed method, reward-weighted regression with sample reuse (R), is demonstrated through robot learning experiments.

ei

Web DOI [BibTex]


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Model Learning in Robotics: a Survey

Nguyen-Tuong, D., Peters, J.

Cognitive Processing, 12(4):319-340, November 2011 (article)

Abstract
Models are among the most essential tools in robotics, such as kinematics and dynamics models of the robot's own body and controllable external objects. It is widely believed that intelligent mammals also rely on internal models in order to generate their actions. However, while classical robotics relies on manually generated models that are based on human insights into physics, future autonomous, cognitive robots need to be able to automatically generate models that are based on information which is extracted from the data streams accessible to the robot. In this paper, we survey the progress in model learning with a strong focus on robot control on a kinematic as well as dynamical level. Here, a model describes essential information about the behavior of the environment and the in uence of an agent on this environment. In the context of model based learning control, we view the model from three di fferent perspectives. First, we need to study the di erent possible model learning architectures for robotics. Second, we discuss what kind of problems these architecture and the domain of robotics imply for the applicable learning methods. From this discussion, we deduce future directions of real-time learning algorithms. Third, we show where these scenarios have been used successfully in several case studies.

ei

PDF [BibTex]

PDF [BibTex]


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FaST linear mixed models for genome-wide association studies

Lippert, C., Listgarten, J., Liu, Y., Kadie, CM., Davidson, RI., Heckerman, D.

Nature Methods, 8(10):833–835, October 2011 (article)

Abstract
We describe factored spectrally transformed linear mixed models (FaST-LMM), an algorithm for genome-wide association studies (GWAS) that scales linearly with cohort size in both run time and memory use. On Wellcome Trust data for 15,000 individuals, FaST-LMM ran an order of magnitude faster than current efficient algorithms. Our algorithm can analyze data for 120,000 individuals in just a few hours, whereas current algorithms fail on data for even 20,000 individuals (http://mscompbio.codeplex.com/).

ei

PDF DOI [BibTex]

PDF DOI [BibTex]


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The effect of noise correlations in populations of diversely tuned neurons

Ecker, A., Berens, P., Tolias, A., Bethge, M.

Journal of Neuroscience, 31(40):14272-14283, October 2011 (article)

Abstract
The amount of information encoded by networks of neurons critically depends on the correlation structure of their activity. Neurons with similar stimulus preferences tend to have higher noise correlations than others. In homogeneous populations of neurons, this limited range correlation structure is highly detrimental to the accuracy of a population code. Therefore, reduced spike count correlations under attention, after adaptation, or after learning have been interpreted as evidence for a more efficient population code. Here, we analyze the role of limited range correlations in more realistic, heterogeneous population models. We use Fisher information and maximum-likelihood decoding to show that reduced correlations do not necessarily improve encoding accuracy. In fact, in populations with more than a few hundred neurons, increasing the level of limited range correlations can substantially improve encoding accuracy. We found that this improvement results from a decrease in noise entropy that is associated with increasing correlations if the marginal distributions are unchanged. Surprisingly, for constant noise entropy and in the limit of large populations, the encoding accuracy is independent of both structure and magnitude of noise correlations.

ei

Web DOI [BibTex]

Web DOI [BibTex]


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Analysis of Fixed-Point and Coordinate Descent Algorithms for Regularized Kernel Methods

Dinuzzo, F.

IEEE Transactions on Neural Networks, 22(10):1576-1587, October 2011 (article)

Abstract
In this paper, we analyze the convergence of two general classes of optimization algorithms for regularized kernel methods with convex loss function and quadratic norm regularization. The first methodology is a new class of algorithms based on fixed-point iterations that are well-suited for a parallel implementation and can be used with any convex loss function. The second methodology is based on coordinate descent, and generalizes some techniques previously proposed for linear support vector machines. It exploits the structure of additively separable loss functions to compute solutions of line searches in closed form. The two methodologies are both very easy to implement. In this paper, we also show how to remove non-differentiability of the objective functional by exactly reformulating a convex regularization problem as an unconstrained differentiable stabilization problem.

ei

Web DOI [BibTex]

Web DOI [BibTex]


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A biomimetic approach to robot table tennis

Mülling, K., Kober, J., Peters, J.

Adaptive Behavior , 19(5):359-376 , October 2011 (article)

Abstract
Playing table tennis is a difficult motor task that requires fast movements, accurate control and adaptation to task parameters. Although human beings see and move slower than most robot systems, they significantly outperform all table tennis robots. One important reason for this higher performance is the human movement generation. In this paper, we study human movements during table tennis and present a robot system that mimics human striking behavior. Our focus lies on generating hitting motions capable of adapting to variations in environmental conditions, such as changes in ball speed and position. Therefore, we model the human movements involved in hitting a table tennis ball using discrete movement stages and the virtual hitting point hypothesis. The resulting model was evaluated both in a physically realistic simulation and on a real anthropomorphic seven degrees of freedom Barrett WAM™ robot arm.

ei

PDF Web DOI [BibTex]

PDF Web DOI [BibTex]


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Whole-genome sequencing of multiple Arabidopsis thaliana populations

Cao, J., Schneeberger, K., Ossowski, S., Günther, T., Bender, S., Fitz, J., Koenig, D., Lanz, C., Stegle, O., Lippert, C., Wang, X., Ott, F., Müller, J., Alonso-Blanco, C., Borgwardt, K., Schmid, K., Weigel, D.

Nature Genetics, 43(10):956–963, October 2011 (article)

Abstract
The plant Arabidopsis thaliana occurs naturally in many different habitats throughout Eurasia. As a foundation for identifying genetic variation contributing to adaptation to diverse environments, a 1001 Genomes Project to sequence geographically diverse A. thaliana strains has been initiated. Here we present the first phase of this project, based on population-scale sequencing of 80 strains drawn from eight regions throughout the species' native range. We describe the majority of common small-scale polymorphisms as well as many larger insertions and deletions in the A. thaliana pan-genome, their effects on gene function, and the patterns of local and global linkage among these variants. The action of processes other than spontaneous mutation is identified by comparing the spectrum of mutations that have accumulated since A. thaliana diverged from its closest relative 10 million years ago with the spectrum observed in the laboratory. Recent species-wide selective sweeps are rare, and potentially deleterious mutations are more common in marginal populations.

ei

Web DOI [BibTex]

Web DOI [BibTex]


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Multiple reference genomes and transcriptomes for Arabidopsis thaliana

Gan, X., Stegle, O., Behr, J., Steffen, J., Drewe, P., Hildebrand, K., Lyngsoe, R., Schultheiss, S., Osborne, E., Sreedharan, V., Kahles, A., Bohnert, R., Jean, G., Derwent, P., Kersey, P., Belfield, E., Harberd, N., Kemen, E., Toomajian, C., Kover, P., Clark, R., Rätsch, G., Mott, R.

Nature, 477(7365):419–423, September 2011 (article)

Abstract
Genetic differences between Arabidopsis thaliana accessions underlie the plant’s extensive phenotypic variation, and until now these have been interpreted largely in the context of the annotated reference accession Col-0. Here we report the sequencing, assembly and annotation of the genomes of 18 natural A. thaliana accessions, and their transcriptomes. When assessed on the basis of the reference annotation, one-third of protein-coding genes are predicted to be disrupted in at least one accession. However, re-annotation of each genome revealed that alternative gene models often restore coding potential. Gene expression in seedlings differed for nearly half of expressed genes and was frequently associated with cis variants within 5 kilobases, as were intron retention alternative splicing events. Sequence and expression variation is most pronounced in genes that respond to the biotic environment. Our data further promote evolutionary and functional studies in A. thaliana, especially the MAGIC genetic reference population descended from these accessions.

ei

Web DOI [BibTex]

Web DOI [BibTex]


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Weisfeiler-Lehman Graph Kernels

Shervashidze, N., Schweitzer, P., van Leeuwen, E., Mehlhorn, K., Borgwardt, M.

Journal of Machine Learning Research, 12, pages: 2539-2561, September 2011 (article)

Abstract
In this article, we propose a family of efficient kernels for large graphs with discrete node labels. Key to our method is a rapid feature extraction scheme based on the Weisfeiler-Lehman test of isomorphism on graphs. It maps the original graph to a sequence of graphs, whose node attributes capture topological and label information. A family of kernels can be defined based on this Weisfeiler-Lehman sequence of graphs, including a highly efficient kernel comparing subtree-like patterns. Its runtime scales only linearly in the number of edges of the graphs and the length of the Weisfeiler-Lehman graph sequence. In our experimental evaluation, our kernels outperform state-of-the-art graph kernels on several graph classification benchmark data sets in terms of accuracy and runtime. Our kernels open the door to large-scale applications of graph kernels in various disciplines such as computational biology and social network analysis.

ei

PDF Web [BibTex]

PDF Web [BibTex]


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What are the Causes of Performance Variation in Brain-Computer Interfacing?

Grosse-Wentrup, M.

International Journal of Bioelectromagnetism, 13(3):115-116, September 2011 (article)

Abstract
While research on brain-computer interfacing (BCI) has seen tremendous progress in recent years, performance still varies substantially between as well as within subjects, with roughly 10 - 20% of subjects being incapable of successfully operating a BCI system. In this short report, I argue that this variation in performance constitutes one of the major obstacles that impedes a successful commercialization of BCI systems. I review the current state of research on the neuro-physiological causes of performance variation in BCI, discuss recent progress and open problems, and delineate potential research programs for addressing this issue.

ei

PDF Web [BibTex]

PDF Web [BibTex]


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Gravitational Lensing Accuracy Testing 2010 (GREAT10) Challenge Handbook

Kitching, T., Amara, A., Gill, M., Harmeling, S., Heymans, C., Massey, R., Rowe, B., Schrabback, T., Voigt, L., Balan, S., Bernstein, G., Bethge, M., Bridle, S., Courbin, F., Gentile, M., Heavens, A., Hirsch, M., Hosseini, R., Kiessling, A., Kirk, D., Kuijken, K., Mandelbaum, R., Moghaddam, B., Nurbaeva, G., Paulin-Henriksson, S., Rassat, A., Rhodes, J., Schölkopf, B., Shawe-Taylor, J., Shmakova, M., Taylor, A., Velander, M., van Waerbeke, L., Witherick, D., Wittman, D.

Annals of Applied Statistics, 5(3):2231-2263, September 2011 (article)

Abstract
GRavitational lEnsing Accuracy Testing 2010 (GREAT10) is a public image analysis challenge aimed at the development of algorithms to analyze astronomical images. Specifically, the challenge is to measure varying image distortions in the presence of a variable convolution kernel, pixelization and noise. This is the second in a series of challenges set to the astronomy, computer science and statistics communities, providing a structured environment in which methods can be improved and tested in preparation for planned astronomical surveys. GREAT10 extends upon previous work by introducing variable fields into the challenge. The “Galaxy Challenge” involves the precise measurement of galaxy shape distortions, quantified locally by two parameters called shear, in the presence of a known convolution kernel. Crucially, the convolution kernel and the simulated gravitational lensing shape distortion both now vary as a function of position within the images, as is the case for real data. In addition, we introduce the “Star Challenge” that concerns the reconstruction of a variable convolution kernel, similar to that in a typical astronomical observation. This document details the GREAT10 Challenge for potential participants. Continually updated information is also available from www.greatchallenges.info.

ei

PDF Web DOI [BibTex]

PDF Web DOI [BibTex]


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MRI-Based Attenuation Correction for Whole-Body PET/MRI: Quantitative Evaluation of Segmentation- and Atlas-Based Methods

Hofmann, M., Bezrukov, I., Mantlik, F., Aschoff, P., Steinke, F., Beyer, T., Pichler, B., Schölkopf, B.

Journal of Nuclear Medicine, 52(9):1392-1399, September 2011 (article)

Abstract
PET/MRI is an emerging dual-modality imaging technology that requires new approaches to PET attenuation correction (AC). We assessed 2 algorithms for whole-body MRI-based AC (MRAC): a basic MR image segmentation algorithm and a method based on atlas registration and pattern recognition (AT&PR). METHODS: Eleven patients each underwent a whole-body PET/CT study and a separate multibed whole-body MRI study. The MR image segmentation algorithm uses a combination of image thresholds, Dixon fat-water segmentation, and component analysis to detect the lungs. MR images are segmented into 5 tissue classes (not including bone), and each class is assigned a default linear attenuation value. The AT&PR algorithm uses a database of previously aligned pairs of MRI/CT image volumes. For each patient, these pairs are registered to the patient MRI volume, and machine-learning techniques are used to predict attenuation values on a continuous scale. MRAC methods are compared via the quantitative analysis of AC PET images using volumes of interest in normal organs and on lesions. We assume the PET/CT values after CT-based AC to be the reference standard. RESULTS: In regions of normal physiologic uptake, the average error of the mean standardized uptake value was 14.1% ± 10.2% and 7.7% ± 8.4% for the segmentation and the AT&PR methods, respectively. Lesion-based errors were 7.5% ± 7.9% for the segmentation method and 5.7% ± 4.7% for the AT&PR method. CONCLUSION: The MRAC method using AT&PR provided better overall PET quantification accuracy than the basic MR image segmentation approach. This better quantification was due to the significantly reduced volume of errors made regarding volumes of interest within or near bones and the slightly reduced volume of errors made regarding areas outside the lungs.

ei

Web DOI [BibTex]


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A human inspired gaze estimation system

Wulff, J., Sinha, P.

Journal of Vision, 11(11):507-507, ARVO, September 2011 (article)

Abstract
Estimating another person's gaze is a crucial skill in human social interactions. The social component is most apparent in dyadic gaze situations, in which the looker seems to look into the eyes of the observer, thereby signaling interest or a turn to speak. In a triadic situation, on the other hand, the looker's gaze is averted from the observer and directed towards another, specific target. This is mostly interpreted as a cue for joint attention, creating awareness of a predator or another point of interest. In keeping with the task's social significance, humans are very proficient at gaze estimation. Our accuracy ranges from less than one degree for dyadic settings to approximately 2.5 degrees for triadic ones. Our goal in this work is to draw inspiration from human gaze estimation mechanisms in order to create an artificial system that can approach the former's accuracy levels. Since human performance is severely impaired by both image-based degradations (Ando, 2004) and a change of facial configurations (Jenkins & Langton, 2003), the underlying principles are believed to be based both on simple image cues such as contrast/brightness distribution and on more complex geometric processing to reconstruct the actual shape of the head. By incorporating both kinds of cues in our system's design, we are able to surpass the accuracy of existing eye-tracking systems, which rely exclusively on either image-based or geometry-based cues (Yamazoe et al., 2008). A side-benefit of this combined approach is that it allows for gaze estimation despite moderate view-point changes. This is important for settings where subjects, say young children or certain kinds of patients, might not be fully cooperative to allow a careful calibration. Our model and implementation of gaze estimation opens up new experimental questions about human mechanisms while also providing a useful tool for general calibration-free, non-intrusive remote eye-tracking.

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link (url) DOI [BibTex]

link (url) DOI [BibTex]


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Detecting synchrony in degraded audio-visual streams

Dhandhania, K., Wulff, J., Sinha, P.

Journal of Vision, 11(11):800-800, ARVO, September 2011 (article)

Abstract
Even 8–10 week old infants, when presented with two dynamic faces and a speech stream, look significantly longer at the ‘correct’ talking person (Patterson & Werker, 2003). This is true even though their reduced visual acuity prevents them from utilizing high spatial frequencies. Computational analyses in the field of audio/video synchrony and automatic speaker detection (e.g. Hershey & Movellan, 2000), in contrast, usually depend on high-resolution images. Therefore, the correlation mechanisms found in these computational studies are not directly applicable to the processes through which we learn to integrate the modalities of speech and vision. In this work, we investigated the correlation between speech signals and degraded video signals. We found a high correlation persisting even with high image degradation, resembling the low visual acuity of young infants. Additionally (in a fashion similar to Graf et al., 2002) we explored which parts of the face correlate with the audio in the degraded video sequences. Perfect synchrony and small offsets in the audio were used while finding the correlation, thereby detecting visual events preceding and following audio events. In order to achieve a sufficiently high temporal resolution, high-speed video sequences (500 frames per second) of talking people were used. This is a temporal resolution unachieved in previous studies and has allowed us to capture very subtle and short visual events. We believe that the results of this study might be interesting not only to vision researchers, but, by revealing subtle effects on a very fine timescale, also to people working in computer graphics and the generation and animation of artificial faces.

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link (url) DOI [BibTex]

link (url) DOI [BibTex]


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Semi-supervised kernel canonical correlation analysis with application to human fMRI

Blaschko, M., Shelton, J., Bartels, A., Lampert, C., Gretton, A.

Pattern Recognition Letters, 32(11):1572-1583 , August 2011 (article)

Abstract
Kernel canonical correlation analysis (KCCA) is a general technique for subspace learning that incorporates principal components analysis (PCA) and Fisher linear discriminant analysis (LDA) as special cases. By finding directions that maximize correlation, KCCA learns representations that are more closely tied to the underlying process that generates the data and can ignore high-variance noise directions. However, for data where acquisition in one or more modalities is expensive or otherwise limited, KCCA may suffer from small sample effects. We propose to use semi-supervised Laplacian regularization to utilize data that are present in only one modality. This approach is able to find highly correlated directions that also lie along the data manifold, resulting in a more robust estimate of correlated subspaces. Functional magnetic resonance imaging (fMRI) acquired data are naturally amenable to subspace techniques as data are well aligned. fMRI data of the human brain are a particularly interesting candidate. In this study we implemented various supervised and semi-supervised versions of KCCA on human fMRI data, with regression to single and multi-variate labels (corresponding to video content subjects viewed during the image acquisition). In each variate condition, the semi-supervised variants of KCCA performed better than the supervised variants, including a supervised variant with Laplacian regularization. We additionally analyze the weights learned by the regression in order to infer brain regions that are important to different types of visual processing.

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PDF PDF DOI [BibTex]


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Multi-subject learning for common spatial patterns in motor-imagery BCI

Devlaminck, D., Wyns, B., Grosse-Wentrup, M., Otte, G., Santens, P.

Computational Intelligence and Neuroscience, 2011(217987):1-9, August 2011 (article)

Abstract
Motor-imagery-based brain-computer interfaces (BCIs) commonly use the common spatial pattern filter (CSP) as preprocessing step before feature extraction and classification. The CSP method is a supervised algorithm and therefore needs subject-specific training data for calibration, which is very time consuming to collect. In order to reduce the amount of calibration data that is needed for a new subject, one can apply multitask (from now on called multisubject) machine learning techniques to the preprocessing phase. Here, the goal of multisubject learning is to learn a spatial filter for a new subject based on its own data and that of other subjects. This paper outlines the details of the multitask CSP algorithm and shows results on two data sets. In certain subjects a clear improvement can be seen, especially when the number of training trials is relatively low.

ei

PDF DOI [BibTex]

PDF DOI [BibTex]