Publications | Max Planck Institute for Intelligent Systems

Micro-manipulation using rotational fluid flows induced by remote magnetic micro-manipulators

Ye, Z., Diller, E., Sitti, M.

Journal of Applied Physics, 112(6):064912, AIP, 2012 (article)

pi Ye, Z., Diller, E., Sitti, M. Micro-manipulation using rotational fluid flows induced by remote magnetic micro-manipulators Journal of Applied Physics, 112(6):064912, AIP, 2012 (article)

Risk-Sensitivity in Bayesian Sensorimotor Integration

Grau-Moya, J, Ortega, PA, Braun, DA

PLoS Computational Biology, 8(9):1-7, sep 2012 (article)

Abstract

Information processing in the nervous system during sensorimotor tasks with inherent uncertainty has been shown to be consistent with Bayesian integration. Bayes optimal decision-makers are, however, risk-neutral in the sense that they weigh all possibilities based on prior expectation and sensory evidence when they choose the action with highest expected value. In contrast, risk-sensitive decision-makers are sensitive to model uncertainty and bias their decision-making processes when they do inference over unobserved variables. In particular, they allow deviations from their probabilistic model in cases where this model makes imprecise predictions. Here we test for risk-sensitivity in a sensorimotor integration task where subjects exhibit Bayesian information integration when they infer the position of a target from noisy sensory feedback. When introducing a cost associated with subjects' response, we found that subjects exhibited a characteristic bias towards low cost responses when their uncertainty was high. This result is in accordance with risk-sensitive decision-making processes that allow for deviations from Bayes optimal decision-making in the face of uncertainty. Our results suggest that both Bayesian integration and risk-sensitivity are important factors to understand sensorimotor integration in a quantitative fashion.

ei Grau-Moya, J, Ortega, PA, Braun, DA Risk-Sensitivity in Bayesian Sensorimotor Integration PLoS Computational Biology, 8(9):1-7, sep 2012 (article)

Accurate dosimetry in scanning transmission X-ray microscopes via the cross-linking threshold dose of poly(methyl methacrylate)

Leontowich, A. F. G., Hitchcock, A. P., Tyliszczak, T., Weigand, M., Wang, J., Karunakaran, C.

{Journal of Synchrotron Radiation}, 19(6):976-987, 2012 (article)

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mms Leontowich, A. F. G., Hitchcock, A. P., Tyliszczak, T., Weigand, M., Wang, J., Karunakaran, C. Accurate dosimetry in scanning transmission X-ray microscopes via the cross-linking threshold dose of poly(methyl methacrylate) {Journal of Synchrotron Radiation}, 19(6):976-987, 2012 (article)

Biogenic potassium salt particles as seeds for secondary organic aerosal in the amazon

Pöhlker, C., Wiedemann, K. T., Sinha, B., Shiraiwa, M., Gunthe, S. S., Smith, M., Su, H., Artaxo, P., Chen, Q., Cheng, Y., Elbert, W., Gilles, M. K., Kilcoyne, A. L. D., Moffet, R. C., Weigand, M., Martin, S. T., Pöschl, U., Andreae, M. O.

{Science}, 337, pages: 1075-1078, 2012 (article)

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mms Pöhlker, C., Wiedemann, K. T., Sinha, B., Shiraiwa, M., Gunthe, S. S., Smith, M., Su, H., Artaxo, P., Chen, Q., Cheng, Y., Elbert, W., Gilles, M. K., Kilcoyne, A. L. D., Moffet, R. C., Weigand, M., Martin, S. T., Pöschl, U., Andreae, M. O. Biogenic potassium salt particles as seeds for secondary organic aerosal in the amazon {Science}, 337, pages: 1075-1078, 2012 (article)

Metal@COFs: Covalent organic frameworks as templates for Pd nanoparticles and hydrogen storage properties of Pd@COF-102 hybrid material

Kalidindi, S. B., Oh, H., Hirscher, M., Esken, D., Wiktor, C., Turner, S., Van Tendeloo, G., Fischer, R. A.

{Chemistry-a European Journal}, 18(35):10848-10856, VCH Verlagsgesellschaft, Weinheim, Germany, 2012 (article)

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mms Kalidindi, S. B., Oh, H., Hirscher, M., Esken, D., Wiktor, C., Turner, S., Van Tendeloo, G., Fischer, R. A. Metal@COFs: Covalent organic frameworks as templates for Pd nanoparticles and hydrogen storage properties of Pd@COF-102 hybrid material {Chemistry-a European Journal}, 18(35):10848-10856, VCH Verlagsgesellschaft, Weinheim, Germany, 2012 (article)

Ion beam lithography for direct patterning of high accuracy large area X-ray elements in gold on membranes

Nadzeyka, A., Peto, L., Bauerdick, S., Mayer, M., Keskinbora, K., Grévent, C., Weigand, M., Hirscher, M., Schütz, G.

{Microelectronic Engineering}, 98, pages: 198-201, 2012 (article)

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mms Nadzeyka, A., Peto, L., Bauerdick, S., Mayer, M., Keskinbora, K., Grévent, C., Weigand, M., Hirscher, M., Schütz, G. Ion beam lithography for direct patterning of high accuracy large area X-ray elements in gold on membranes {Microelectronic Engineering}, 98, pages: 198-201, 2012 (article)

Remotely addressable magnetic composite micropumps

Diller, E., Miyashita, S., Sitti, M.

Rsc Advances, 2(9):3850-3856, Royal Society of Chemistry, 2012 (article)

pi Diller, E., Miyashita, S., Sitti, M. Remotely addressable magnetic composite micropumps Rsc Advances, 2(9):3850-3856, Royal Society of Chemistry, 2012 (article)

Micro- and nanoscale fluid flow on chemical channels

Dörfler, Fabian, Rauscher, Markus, Koplik, Joel, Harting, Jens, Dietrich, S.

{Soft Matter}, 8(35):9221-9234, 2012 (article)

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link (url) DOI [BibTex]

mms Dörfler, Fabian, Rauscher, Markus, Koplik, Joel, Harting, Jens, Dietrich, S. Micro- and nanoscale fluid flow on chemical channels {Soft Matter}, 8(35):9221-9234, 2012 (article)

link (url) DOI [BibTex]

Novel characterization of the adsorption sites in large pore Metal-Organic Frameworks: Combination of X-ray powder diffraction and thermal desorption spectroscopy

Soleimani Dorcheh, A., Dinnebier, R. E., Kuc, A., Magdysyuk, O., Adams, F., Denysenko, D., Heine, T., Volkmer, D., Donner, W., Hirscher, M.

{Physical Chemistry Chemical Physics}, 14(37):12892-12897, 2012 (article)

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mms Soleimani Dorcheh, A., Dinnebier, R. E., Kuc, A., Magdysyuk, O., Adams, F., Denysenko, D., Heine, T., Volkmer, D., Donner, W., Hirscher, M. Novel characterization of the adsorption sites in large pore Metal-Organic Frameworks: Combination of X-ray powder diffraction and thermal desorption spectroscopy {Physical Chemistry Chemical Physics}, 14(37):12892-12897, 2012 (article)

Tunnel contacts for spin injection into silicon: The Si-Co interface with and without a MgO tunnel barrier - A study by high-resolution Rutherford backscattering

Dash, S. P., Goll, D., Kopold, P., Carstanjen, H. D.

{Advances in Materials Science and Engineering}, 2012, 2012 (article)

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mms Dash, S. P., Goll, D., Kopold, P., Carstanjen, H. D. Tunnel contacts for spin injection into silicon: The Si-Co interface with and without a MgO tunnel barrier - A study by high-resolution Rutherford backscattering {Advances in Materials Science and Engineering}, 2012, 2012 (article)

Fast spin-wave-mediated magnetic vortex core reversal

Kammerer, M., Stoll, H., Noske, M., Sproll, M., Weigand, M., Illg, C., Woltersdorf, G., Fähnle, M., Back, C., Schütz, G.

{Physical Review B}, 86(13), 2012 (article)

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mms Kammerer, M., Stoll, H., Noske, M., Sproll, M., Weigand, M., Illg, C., Woltersdorf, G., Fähnle, M., Back, C., Schütz, G. Fast spin-wave-mediated magnetic vortex core reversal {Physical Review B}, 86(13), 2012 (article)

Deformation-driven formation of equilibrium phases in the Cu-Ni alloys

Straumal, B. B., Protasova, S. G., Mazilkin, A. A., Rabkin, E., Goll, D., Schütz, G., Baretzky, B., Valiev, R. Z.

{Journal of Materials Science}, 47, pages: 360-367, 2012 (article)

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mms Straumal, B. B., Protasova, S. G., Mazilkin, A. A., Rabkin, E., Goll, D., Schütz, G., Baretzky, B., Valiev, R. Z. Deformation-driven formation of equilibrium phases in the Cu-Ni alloys {Journal of Materials Science}, 47, pages: 360-367, 2012 (article)

Nanosponges for hydrogen storage

Schlichtenmayer, M., Hirscher, M.

{Journal of Materials Chemistry}, 22, pages: 10134-10143, 2012 (article)

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mms Schlichtenmayer, M., Hirscher, M. Nanosponges for hydrogen storage {Journal of Materials Chemistry}, 22, pages: 10134-10143, 2012 (article)

Magnetic and electronic properties of the interface between half metallic Fe3O4 and semiconducting ZnO

Brück, S., Paul, M., Tian, H., Müller, A., Kufer, D., Praetorius, C., Fauth, K., Audehm, P., Goering, E., Verbeeck, J., Van Tendeloo, G., Sing, M., Claessen, R.

{Applied Physics Letters}, 100, 2012 (article)

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mms Brück, S., Paul, M., Tian, H., Müller, A., Kufer, D., Praetorius, C., Fauth, K., Audehm, P., Goering, E., Verbeeck, J., Van Tendeloo, G., Sing, M., Claessen, R. Magnetic and electronic properties of the interface between half metallic Fe3O4 and semiconducting ZnO {Applied Physics Letters}, 100, 2012 (article)

Amorphous interlayers between crystalline grains in ferromagnetic ZnO films

Straumal, B. B., Protasova, S. G., Mazilkin, A. A., Baretzky, B., Myatiev, A. A., Straumal, P. B., Tietze, T., Schütz, G., Goering, E.

{Materials Letters}, 71, pages: 21-24, 2012 (article)

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mms Straumal, B. B., Protasova, S. G., Mazilkin, A. A., Baretzky, B., Myatiev, A. A., Straumal, P. B., Tietze, T., Schütz, G., Goering, E. Amorphous interlayers between crystalline grains in ferromagnetic ZnO films {Materials Letters}, 71, pages: 21-24, 2012 (article)

Model-free reinforcement learning of impedance control in stochastic environments

Stulp, Freek, Buchli, Jonas, Ellmer, Alice, Mistry, Michael, Theodorou, Evangelos A., Schaal, S.

Autonomous Mental Development, IEEE Transactions on, 4(4):330-341, 2012 (article)

am Stulp, Freek, Buchli, Jonas, Ellmer, Alice, Mistry, Michael, Theodorou, Evangelos A., Schaal, S. Model-free reinforcement learning of impedance control in stochastic environments Autonomous Mental Development, IEEE Transactions on, 4(4):330-341, 2012 (article)

Shape-Programmable Soft Capsule Robots for Semi-Implantable Drug Delivery

Yim, S., Sitti, M.

Mechatronics, IEEE/ASME Transactions on, 2012 (article)

pi Yim, S., Sitti, M. Shape-Programmable Soft Capsule Robots for Semi-Implantable Drug Delivery Mechatronics, IEEE/ASME Transactions on, 2012 (article)

Control of multiple heterogeneous magnetic microrobots in two dimensions on nonspecialized surfaces

Diller, E., Floyd, S., Pawashe, C., Sitti, M.

IEEE Transactions on Robotics, 28(1):172-182, IEEE, 2012 (article)

pi Diller, E., Floyd, S., Pawashe, C., Sitti, M. Control of multiple heterogeneous magnetic microrobots in two dimensions on nonspecialized surfaces IEEE Transactions on Robotics, 28(1):172-182, IEEE, 2012 (article)

Gecko-Inspired Controllable Adhesive Structures Applied to Micromanipulation

Mengüç, Y., Yang, S. Y., Kim, S., Rogers, J. A., Sitti, M.

Advanced Functional Materials, 22(6):1245-1245, WILEY-VCH Verlag, 2012 (article)

pi Mengüç, Y., Yang, S. Y., Kim, S., Rogers, J. A., Sitti, M. Gecko-Inspired Controllable Adhesive Structures Applied to Micromanipulation Advanced Functional Materials, 22(6):1245-1245, WILEY-VCH Verlag, 2012 (article)

Elastomer surfaces with directionally dependent adhesion strength and their use in transfer printing with continuous roll-to-roll applications

Yang, S. Y., Carlson, A., Cheng, H., Yu, Q., Ahmed, N., Wu, J., Kim, S., Sitti, M., Ferreira, P. M., Huang, Y., others,

Advanced Materials, 24(16):2117-2122, WILEY-VCH Verlag, 2012 (article)

pi Yang, S. Y., Carlson, A., Cheng, H., Yu, Q., Ahmed, N., Wu, J., Kim, S., Sitti, M., Ferreira, P. M., Huang, Y., others, Elastomer surfaces with directionally dependent adhesion strength and their use in transfer printing with continuous roll-to-roll applications Advanced Materials, 24(16):2117-2122, WILEY-VCH Verlag, 2012 (article)

Effect of retraction speed on adhesion of elastomer fibrillar structures

Abusomwan, U., Sitti, M.

Applied Physics Letters, 101(21):211907, AIP, 2012 (article)

pi Abusomwan, U., Sitti, M. Effect of retraction speed on adhesion of elastomer fibrillar structures Applied Physics Letters, 101(21):211907, AIP, 2012 (article)

Burn-in, bias, and the rationality of anchoring

Lieder, F., Griffiths, T. L., Goodman, N. D.

Advances in Neural Information Processing Systems 25, pages: 2699-2707, 2012 (article)

re Lieder, F., Griffiths, T. L., Goodman, N. D. Burn-in, bias, and the rationality of anchoring Advances in Neural Information Processing Systems 25, pages: 2699-2707, 2012 (article)

Accelerated diffusion and phase transformations in Co-Cu alloys driven by the severe plastic deformation

Straumal, B. B., Mazilkin, A. A., Baretzky, B., Schütz, G., Rabkin, E., Valiev, R. Z.

{Special Issue on Advanced Materials Science in Bulk Nanostructured Metals}, 53(1):63-71, 2012 (article)

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mms Straumal, B. B., Mazilkin, A. A., Baretzky, B., Schütz, G., Rabkin, E., Valiev, R. Z. Accelerated diffusion and phase transformations in Co-Cu alloys driven by the severe plastic deformation {Special Issue on Advanced Materials Science in Bulk Nanostructured Metals}, 53(1):63-71, 2012 (article)

Unusual flux jumps above 12 K in non-homogeneous MgB2 thin films

Treiber, S., Stahl, C., Schütz, G., Albrecht, J.

{Superconductor Science \& Technology}, 25, 2012 (article)

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mms Treiber, S., Stahl, C., Schütz, G., Albrecht, J. Unusual flux jumps above 12 K in non-homogeneous MgB2 thin films {Superconductor Science \& Technology}, 25, 2012 (article)

Ferromagnetism of nanostructured zinc oxide films

Straumal, B. B., Mazilkin, A. A., Protasova, S. G., Straumal, P. B., Myatiev, A. A., Schütz, G., Goering, E., Baretzky, B.

{The Physics of Metals and Metallography}, 113(13):1244-1256, 2012 (article)

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mms Straumal, B. B., Mazilkin, A. A., Protasova, S. G., Straumal, P. B., Myatiev, A. A., Schütz, G., Goering, E., Baretzky, B. Ferromagnetism of nanostructured zinc oxide films {The Physics of Metals and Metallography}, 113(13):1244-1256, 2012 (article)

Frequencies and polarization vectors of phonons: Results from force constants which are fitted to experimental data or calculated ab initio

Illg, C., Meyer, B., Fähnle, M.

{Physical Review B}, 86(17), Published by the American Physical Society through the American Institute of Physics, Woodbury, NY, 2012 (article)

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mms Illg, C., Meyer, B., Fähnle, M. Frequencies and polarization vectors of phonons: Results from force constants which are fitted to experimental data or calculated ab initio {Physical Review B}, 86(17), Published by the American Physical Society through the American Institute of Physics, Woodbury, NY, 2012 (article)

Grain boundary wetting by a second solid phase in the Zr-Nb alloys

Straumal, B. B., Gornakova, A. S., Kucheev, Y. O., Baretzky, B., Nekrasov, A. N.

{Journal of Materials Engineering and Performance}, 21(5):721-724, 2012 (article)

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mms Straumal, B. B., Gornakova, A. S., Kucheev, Y. O., Baretzky, B., Nekrasov, A. N. Grain boundary wetting by a second solid phase in the Zr-Nb alloys {Journal of Materials Engineering and Performance}, 21(5):721-724, 2012 (article)

Grain boundary wetting in the NdFeB-based hard magnetic alloys

Straumal, B. B., Kucheev, Y. O., Yatskovskaya, I. L., Mogilnikova, I. V., Schütz, G., Nekrasov, A. N., Baretzky, B.

{Journal of Materials Science}, 47(24):8352-8359, 2012 (article)

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mms Straumal, B. B., Kucheev, Y. O., Yatskovskaya, I. L., Mogilnikova, I. V., Schütz, G., Nekrasov, A. N., Baretzky, B. Grain boundary wetting in the NdFeB-based hard magnetic alloys {Journal of Materials Science}, 47(24):8352-8359, 2012 (article)

Publishers site Code PDF [BibTex]

Natural Metrics and Least-Committed Priors for Articulated Tracking

Soren Hauberg, Stefan Sommer, Kim S. Pedersen

Image and Vision Computing, 30(6-7):453-461, Elsevier, 2012 (article)

ps Soren Hauberg, Stefan Sommer, Kim S. Pedersen Natural Metrics and Least-Committed Priors for Articulated Tracking Image and Vision Computing, 30(6-7):453-461, Elsevier, 2012 (article)

Publishers site Code PDF [BibTex]

Reinforcement Learning with Sequences of Motion Primitives for Robust Manipulation

Stulp, F., Theodorou, E., Schaal, S.

IEEE Transactions on Robotics, 2012 (article)

am Stulp, F., Theodorou, E., Schaal, S. Reinforcement Learning with Sequences of Motion Primitives for Robust Manipulation IEEE Transactions on Robotics, 2012 (article)

Impact and Surface Tension in Water: a Study of Landing Bodies

Shih, B., Laham, L., Lee, K. J., Krasnoff, N., Diller, E., Sitti, M.

Bio-inspired Robotics Final Project, Carnegie Mellon University, 2012 (article)

pi Shih, B., Laham, L., Lee, K. J., Krasnoff, N., Diller, E., Sitti, M. Impact and Surface Tension in Water: a Study of Landing Bodies Bio-inspired Robotics Final Project, Carnegie Mellon University, 2012 (article)

Design and rolling locomotion of a magnetically actuated soft capsule endoscope

Yim, S., Sitti, M.

IEEE Transactions on Robotics, 28(1):183-194, IEEE, 2012 (article)

pi Yim, S., Sitti, M. Design and rolling locomotion of a magnetically actuated soft capsule endoscope IEEE Transactions on Robotics, 28(1):183-194, IEEE, 2012 (article)

Design and manufacturing of a controllable miniature flapping wing robotic platform

Arabagi, V., Hines, L., Sitti, M.

The International Journal of Robotics Research, 31(6):785-800, SAGE Publications Sage UK: London, England, 2012 (article)

pi Arabagi, V., Hines, L., Sitti, M. Design and manufacturing of a controllable miniature flapping wing robotic platform The International Journal of Robotics Research, 31(6):785-800, SAGE Publications Sage UK: London, England, 2012 (article)

Chemotactic steering of bacteria propelled microbeads

Kim, D., Liu, A., Diller, E., Sitti, M.

Biomedical microdevices, 14(6):1009-1017, Springer US, 2012 (article)

pi Kim, D., Liu, A., Diller, E., Sitti, M. Chemotactic steering of bacteria propelled microbeads Biomedical microdevices, 14(6):1009-1017, Springer US, 2012 (article)

Construct Validity of Instrument Vibrations as a Measure of Robotic Surgical Skill

Gomez, E. D., Bark, K., Rivera, C., McMahan, W., Remington, A., Lee, D. I., Williams, N., Murayama, K., Dumon, K., Kuchenbecker, K. J.

Journal of the American College of Surgeons, 215(3):S119-120, Chicago, Illinois, USA, 2012, Oral presentation given by Gomez at the {\em American College of Surgeons (ACS) Clinical Congress} (article)

hi Gomez, E. D., Bark, K., Rivera, C., McMahan, W., Remington, A., Lee, D. I., Williams, N., Murayama, K., Dumon, K., Kuchenbecker, K. J. Construct Validity of Instrument Vibrations as a Measure of Robotic Surgical Skill Journal of the American College of Surgeons, 215(3):S119-120, Chicago, Illinois, USA, 2012, Oral presentation given by Gomez at the {\em American College of Surgeons (ACS) Clinical Congress} (article)

Hydrogel microrobots actuated by optically generated vapour bubbles

Hu, W., Ishii, K. S., Fan, Q., Ohta, A. T.

Lab on a Chip, 12(19):3821-3826, Royal Society of Chemistry, 2012 (article)

pi Hu, W., Ishii, K. S., Fan, Q., Ohta, A. T. Hydrogel microrobots actuated by optically generated vapour bubbles Lab on a Chip, 12(19):3821-3826, Royal Society of Chemistry, 2012 (article)

Magnetic proximity effect in YBa2Cu3O7 / La2/3Ca1/3MnO3 and YBa2Cu3O7 / LaMnO3+δsuperlattices

Satapathy, D. K., Uribe-Laverde, M. A., Marozau, I., Malik, V. K., Das, S., Wagner, T., Marcelot, C., Stahn, J., Brück, S., Rühm, A., Macke, S., Tietze, T., Goering, E., Frañó, A., Kim, J., Wu, M., Benckiser, E., Keimer, B., Devishvili, A., Toperverg, B. P., Merz, M., Nagel, P., Schuppler, S., Bernhard, C.

{Physical Review Letters}, 108, 2012 (article)

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mms Satapathy, D. K., Uribe-Laverde, M. A., Marozau, I., Malik, V. K., Das, S., Wagner, T., Marcelot, C., Stahn, J., Brück, S., Rühm, A., Macke, S., Tietze, T., Goering, E., Frañó, A., Kim, J., Wu, M., Benckiser, E., Keimer, B., Devishvili, A., Toperverg, B. P., Merz, M., Nagel, P., Schuppler, S., Bernhard, C. Magnetic proximity effect in YBa2Cu3O7 / La2/3Ca1/3MnO3 and YBa2Cu3O7 / LaMnO3+δsuperlattices {Physical Review Letters}, 108, 2012 (article)

Noble gases and microporous frameworks; from interaction to application

Soleimani Dorcheh, A., Denysenko, D., Volkmer, D., Donner, W., Hirscher, M.

{Microporous and Mesoporous Materials}, 162, pages: 64-68, Elsevier, Amsterdam, 2012 (article)

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mms Soleimani Dorcheh, A., Denysenko, D., Volkmer, D., Donner, W., Hirscher, M. Noble gases and microporous frameworks; from interaction to application {Microporous and Mesoporous Materials}, 162, pages: 64-68, Elsevier, Amsterdam, 2012 (article)

Note: Unique characterization possibilities in the ultra high vacuum scanning transmission x-ray microscope (UHV-STXM) "MAXYMUS" using a rotatable permanent magnetic field up to 0.22 T

Nolle, D., Weigand, M., Audehm, P., Goering, E., Wiesemann, U., Wolter, C., Nolle, E., Schütz, G.

{Review of Scientific Instruments}, 83(4), 2012 (article)

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mms Nolle, D., Weigand, M., Audehm, P., Goering, E., Wiesemann, U., Wolter, C., Nolle, E., Schütz, G. Note: Unique characterization possibilities in the ultra high vacuum scanning transmission x-ray microscope (UHV-STXM) "MAXYMUS" using a rotatable permanent magnetic field up to 0.22 T {Review of Scientific Instruments}, 83(4), 2012 (article)

Microstructure and superconducting properties of MgB2 films prepared by solid state reaction of multilayer precursors of the elements

Kugler, B., Stahl, C., Treiber, S., Soltan, S., Haug, S., Schütz, G., Albrecht, J.

{Thin Solid Films}, 520, pages: 6985-6988, 2012 (article)

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mms Kugler, B., Stahl, C., Treiber, S., Soltan, S., Haug, S., Schütz, G., Albrecht, J. Microstructure and superconducting properties of MgB2 films prepared by solid state reaction of multilayer precursors of the elements {Thin Solid Films}, 520, pages: 6985-6988, 2012 (article)

2007

HPLC analysis and pharmacokinetic study of quercitrin and isoquercitrin in rat plasma after administration of Hypericum japonicum thunb. extract.

Li, J., Wang, W., Zhang, L., Chen, H., Bi, S.

Biomedical Chromatography, 22(4):374-378, December 2007 (article)

Abstract

A simple HPLC method was developed for determination of quercitrin and isoquercitrin in rat plasma. Reversed-phase HPLC was employed for the quantitative analysis using kaempferol-3-O--d-glucopyranoside-7-O--l-rhamnoside as an internal standard. Following extraction from the plasma samples with ethyl acetate-isopropanol (95:5, v/v), these two compounds were successfully separated on a Luna C18 column (250 × 4.6 mm, 5 µm) with isocratic elution of acetonitrile-0.5% aqueous acetic acid (17:83, v/v) as the mobile phase. The flow-rate was set at 1 mL/min and the eluent was detected at 350 nm for both quercitrin and isoquercitrin. The method was linear over the studied ranges of 50-6000 and 50-5000 ng/mL for quercitrin and isoquercitrin, respectively. The intra- and inter-day precisions of the analysis were better than 13.1 and 13.2%, respectively. The lower limits of quantitation for quercitrin and isoquercitrin in plasma were both of 50 ng/mL. The mean extraction recoveries were 73 and 61% for quercitrin and i soquercitrin, respectively. The validated method was successfully applied to pharmacokinetic studies of the two analytes in rat plasma after the oral administration of Hypericum japonicum thunb. ethanol extract.

2007

ei Li, J., Wang, W., Zhang, L., Chen, H., Bi, S. HPLC analysis and pharmacokinetic study of quercitrin and isoquercitrin in rat plasma after administration of Hypericum japonicum thunb. extract. Biomedical Chromatography, 22(4):374-378, December 2007 (article)

Graph sharpening plus graph integration: a synergy that improves protein functional classification

Shin, HH., Lisewski, AM., Lichtarge, O.

Bioinformatics, 23(23):3217-3224, December 2007 (article)

ei Shin, HH., Lisewski, AM., Lichtarge, O. Graph sharpening plus graph integration: a synergy that improves protein functional classification Bioinformatics, 23(23):3217-3224, December 2007 (article)

A Tutorial on Spectral Clustering

von Luxburg, U.

Statistics and Computing, 17(4):395-416, December 2007 (article)

Abstract

In recent years, spectral clustering has become one of the most popular modern clustering algorithms. It is simple to implement, can be solved efficiently by standard linear algebra software, and very often outperforms traditional clustering algorithms such as the k-means algorithm. On the first glance spectral clustering appears slightly mysterious, and it is not obvious to see why it works at all and what it really does. The goal of this tutorial is to give some intuition on those questions. We describe different graph Laplacians and their basic properties, present the most common spectral clustering algorithms, and derive those algorithms from scratch by several different approaches. Advantages and disadvantages of the different spectral clustering algorithms are discussed.

ei von Luxburg, U. A Tutorial on Spectral Clustering Statistics and Computing, 17(4):395-416, December 2007 (article)

Jäkel, F., Schölkopf, B., Wichmann, F.

A Tutorial on Kernel Methods for Categorization

Journal of Mathematical Psychology, 51(6):343-358, December 2007 (article)

Abstract

The abilities to learn and to categorize are fundamental for cognitive systems, be it animals or machines, and therefore have attracted attention from engineers and psychologists alike. Modern machine learning methods and psychological models of categorization are remarkably similar, partly because these two fields share a common history in artificial neural networks and reinforcement learning. However, machine learning is now an independent and mature field that has moved beyond psychologically or neurally inspired algorithms towards providing foundations for a theory of learning that is rooted in statistics and functional analysis. Much of this research is potentially interesting for psychological theories of learning and categorization but also hardly accessible for psychologists. Here, we provide a tutorial introduction to a popular class of machine learning tools, called kernel methods. These methods are closely related to perceptrons, radial-basis-function neural networks and exemplar theories of catego rization. Recent theoretical advances in machine learning are closely tied to the idea that the similarity of patterns can be encapsulated in a positive definite kernel. Such a positive definite kernel can define a reproducing kernel Hilbert space which allows one to use powerful tools from functional analysis for the analysis of learning algorithms. We give basic explanations of some key conceptsthe so-called kernel trick, the representer theorem and regularizationwhich may open up the possibility that insights from machine learning can feed back into psychology.

PDF Web DOI [BibTex]

ei Jäkel, F., Schölkopf, B., Wichmann, F. A Tutorial on Kernel Methods for Categorization Journal of Mathematical Psychology, 51(6):343-358, December 2007 (article)

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A semigroup approach to queueing systems

Haji, A., Radl, A.

Semigroup Forum, 75(3):610-624, December 2007 (article)

Abstract

We prove asymptotic stability of the solutions of equations describing a simple queueing system consisting of two machines separated by a finite storage buffer. Following an approach by G. Gupur, we apply the theory of C0-semigroups and spectral theory of positive operators.

ei Haji, A., Radl, A. A semigroup approach to queueing systems Semigroup Forum, 75(3):610-624, December 2007 (article)

Point-spread functions for backscattered imaging in the scanning electron microscope

Hennig, P., Denk, W.

Journal of Applied Physics , 102(12):1-8, December 2007 (article)

Abstract

One knows the imaging system's properties are central to the correct interpretation of any image. In a scanning electron microscope regions of different composition generally interact in a highly nonlinear way during signal generation. Using Monte Carlo simulations we found that in resin-embedded, heavy metal-stained biological specimens staining is sufficiently dilute to allow an approximately linear treatment. We then mapped point-spread functions for backscattered-electron contrast, for primary energies of 3 and 7 keV and for different detector specifications. The point-spread functions are surprisingly well confined (both laterally and in depth) compared even to the distribution of only those scattered electrons that leave the sample again.

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ei pn Hennig, P., Denk, W. Point-spread functions for backscattered imaging in the scanning electron microscope Journal of Applied Physics , 102(12):1-8, December 2007 (article)

Accurate Splice site Prediction Using Support Vector Machines

Sonnenburg, S., Schweikert, G., Philips, P., Behr, J., Rätsch, G.

BMC Bioinformatics, 8(Supplement 10):1-16, December 2007 (article)

Abstract

Background: For splice site recognition, one has to solve two classification problems: discriminating true from decoy splice sites for both acceptor and donor sites. Gene finding systems typically rely on Markov Chains to solve these tasks. Results: In this work we consider Support Vector Machines for splice site recognition. We employ the so-called weighted degree kernel which turns out well suited for this task, as we will illustrate in several experiments where we compare its prediction accuracy with that of recently proposed systems. We apply our method to the genome-wide recognition of splice sites in Caenorhabditis elegans, Drosophila melanogaster, Arabidopsis thaliana, Danio rerio, and Homo sapiens. Our performance estimates indicate that splice sites can be recognized very accurately in these genomes and that our method outperforms many other methods including Markov Chains, GeneSplicer and SpliceMachine. We provide genome-wide predictions of splice sites and a stand-alone prediction tool ready to be used for incorporation in a gene finder. Availability: Data, splits, additional information on the model selection, the whole genome predictions, as well as the stand-alone prediction tool are available for download at http:// www.fml.mpg.de/raetsch/projects/splice.

ei Sonnenburg, S., Schweikert, G., Philips, P., Behr, J., Rätsch, G. Accurate Splice site Prediction Using Support Vector Machines BMC Bioinformatics, 8(Supplement 10):1-16, December 2007 (article)

Experimental design for efficient identification of gene regulatory networks using sparse Bayesian models

Steinke, F., Seeger, M., Tsuda, K.

BMC Systems Biology, 1(51):1-15, November 2007 (article)

ei Steinke, F., Seeger, M., Tsuda, K. Experimental design for efficient identification of gene regulatory networks using sparse Bayesian models BMC Systems Biology, 1(51):1-15, November 2007 (article)

A unifying framework for robot control with redundant DOFs

Peters, J., Mistry, M., Udwadia, F., Nakanishi, J., Schaal, S.

Autonomous Robots, 24(1):1-12, October 2007 (article)

Abstract

Recently, Udwadia (Proc. R. Soc. Lond. A 2003:17831800, 2003) suggested to derive tracking controllers for mechanical systems with redundant degrees-of-freedom (DOFs) using a generalization of Gauss principle of least constraint. This method allows reformulating control problems as a special class of optimal controllers. In this paper, we take this line of reasoning one step further and demonstrate that several well-known and also novel nonlinear robot control laws can be derived from this generic methodology. We show experimental verifications on a Sarcos Master Arm robot for some of the derived controllers. The suggested approach offers a promising unification and simplification of nonlinear control law design for robots obeying rigid body dynamics equations, both with or without external constraints, with over-actuation or underactuation, as well as open-chain and closed-chain kinematics.

ei Peters, J., Mistry, M., Udwadia, F., Nakanishi, J., Schaal, S. A unifying framework for robot control with redundant DOFs Autonomous Robots, 24(1):1-12, October 2007 (article)