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2012


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Ion beam lithography for direct patterning of high accuracy large area X-ray elements in gold on membranes

Nadzeyka, A., Peto, L., Bauerdick, S., Mayer, M., Keskinbora, K., Grévent, C., Weigand, M., Hirscher, M., Schütz, G.

{Microelectronic Engineering}, 98, pages: 198-201, 2012 (article)

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DOI [BibTex]

2012


DOI [BibTex]


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Remotely addressable magnetic composite micropumps

Diller, E., Miyashita, S., Sitti, M.

Rsc Advances, 2(9):3850-3856, Royal Society of Chemistry, 2012 (article)

pi

[BibTex]

[BibTex]


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Micro- and nanoscale fluid flow on chemical channels

Dörfler, Fabian, Rauscher, Markus, Koplik, Joel, Harting, Jens, Dietrich, S.

{Soft Matter}, 8(35):9221-9234, 2012 (article)

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link (url) DOI [BibTex]

link (url) DOI [BibTex]


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Novel characterization of the adsorption sites in large pore Metal-Organic Frameworks: Combination of X-ray powder diffraction and thermal desorption spectroscopy

Soleimani Dorcheh, A., Dinnebier, R. E., Kuc, A., Magdysyuk, O., Adams, F., Denysenko, D., Heine, T., Volkmer, D., Donner, W., Hirscher, M.

{Physical Chemistry Chemical Physics}, 14(37):12892-12897, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Tunnel contacts for spin injection into silicon: The Si-Co interface with and without a MgO tunnel barrier - A study by high-resolution Rutherford backscattering

Dash, S. P., Goll, D., Kopold, P., Carstanjen, H. D.

{Advances in Materials Science and Engineering}, 2012, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Fast spin-wave-mediated magnetic vortex core reversal

Kammerer, M., Stoll, H., Noske, M., Sproll, M., Weigand, M., Illg, C., Woltersdorf, G., Fähnle, M., Back, C., Schütz, G.

{Physical Review B}, 86(13), 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Deformation-driven formation of equilibrium phases in the Cu-Ni alloys

Straumal, B. B., Protasova, S. G., Mazilkin, A. A., Rabkin, E., Goll, D., Schütz, G., Baretzky, B., Valiev, R. Z.

{Journal of Materials Science}, 47, pages: 360-367, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Nanosponges for hydrogen storage

Schlichtenmayer, M., Hirscher, M.

{Journal of Materials Chemistry}, 22, pages: 10134-10143, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Magnetic and electronic properties of the interface between half metallic Fe3O4 and semiconducting ZnO

Brück, S., Paul, M., Tian, H., Müller, A., Kufer, D., Praetorius, C., Fauth, K., Audehm, P., Goering, E., Verbeeck, J., Van Tendeloo, G., Sing, M., Claessen, R.

{Applied Physics Letters}, 100, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Amorphous interlayers between crystalline grains in ferromagnetic ZnO films

Straumal, B. B., Protasova, S. G., Mazilkin, A. A., Baretzky, B., Myatiev, A. A., Straumal, P. B., Tietze, T., Schütz, G., Goering, E.

{Materials Letters}, 71, pages: 21-24, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Model-free reinforcement learning of impedance control in stochastic environments

Stulp, Freek, Buchli, Jonas, Ellmer, Alice, Mistry, Michael, Theodorou, Evangelos A., Schaal, S.

Autonomous Mental Development, IEEE Transactions on, 4(4):330-341, 2012 (article)

am

[BibTex]

[BibTex]


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Shape-Programmable Soft Capsule Robots for Semi-Implantable Drug Delivery

Yim, S., Sitti, M.

Mechatronics, IEEE/ASME Transactions on, 2012 (article)

pi

Project Page [BibTex]

Project Page [BibTex]


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Control of multiple heterogeneous magnetic microrobots in two dimensions on nonspecialized surfaces

Diller, E., Floyd, S., Pawashe, C., Sitti, M.

IEEE Transactions on Robotics, 28(1):172-182, IEEE, 2012 (article)

pi

[BibTex]

[BibTex]


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Gecko-Inspired Controllable Adhesive Structures Applied to Micromanipulation

Mengüç, Y., Yang, S. Y., Kim, S., Rogers, J. A., Sitti, M.

Advanced Functional Materials, 22(6):1245-1245, WILEY-VCH Verlag, 2012 (article)

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Project Page [BibTex]

Project Page [BibTex]


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Elastomer surfaces with directionally dependent adhesion strength and their use in transfer printing with continuous roll-to-roll applications

Yang, S. Y., Carlson, A., Cheng, H., Yu, Q., Ahmed, N., Wu, J., Kim, S., Sitti, M., Ferreira, P. M., Huang, Y., others,

Advanced Materials, 24(16):2117-2122, WILEY-VCH Verlag, 2012 (article)

pi

[BibTex]

[BibTex]


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Effect of retraction speed on adhesion of elastomer fibrillar structures

Abusomwan, U., Sitti, M.

Applied Physics Letters, 101(21):211907, AIP, 2012 (article)

pi

Project Page [BibTex]

Project Page [BibTex]


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Accelerated diffusion and phase transformations in Co-Cu alloys driven by the severe plastic deformation

Straumal, B. B., Mazilkin, A. A., Baretzky, B., Schütz, G., Rabkin, E., Valiev, R. Z.

{Special Issue on Advanced Materials Science in Bulk Nanostructured Metals}, 53(1):63-71, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Unusual flux jumps above 12 K in non-homogeneous MgB2 thin films

Treiber, S., Stahl, C., Schütz, G., Albrecht, J.

{Superconductor Science \& Technology}, 25, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Ferromagnetism of nanostructured zinc oxide films

Straumal, B. B., Mazilkin, A. A., Protasova, S. G., Straumal, P. B., Myatiev, A. A., Schütz, G., Goering, E., Baretzky, B.

{The Physics of Metals and Metallography}, 113(13):1244-1256, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Frequencies and polarization vectors of phonons: Results from force constants which are fitted to experimental data or calculated ab initio

Illg, C., Meyer, B., Fähnle, M.

{Physical Review B}, 86(17), Published by the American Physical Society through the American Institute of Physics, Woodbury, NY, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Grain boundary wetting by a second solid phase in the Zr-Nb alloys

Straumal, B. B., Gornakova, A. S., Kucheev, Y. O., Baretzky, B., Nekrasov, A. N.

{Journal of Materials Engineering and Performance}, 21(5):721-724, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Grain boundary wetting in the NdFeB-based hard magnetic alloys

Straumal, B. B., Kucheev, Y. O., Yatskovskaya, I. L., Mogilnikova, I. V., Schütz, G., Nekrasov, A. N., Baretzky, B.

{Journal of Materials Science}, 47(24):8352-8359, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Reinforcement Learning with Sequences of Motion Primitives for Robust Manipulation

Stulp, F., Theodorou, E., Schaal, S.

IEEE Transactions on Robotics, 2012 (article)

am

[BibTex]

[BibTex]


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Impact and Surface Tension in Water: a Study of Landing Bodies

Shih, B., Laham, L., Lee, K. J., Krasnoff, N., Diller, E., Sitti, M.

Bio-inspired Robotics Final Project, Carnegie Mellon University, 2012 (article)

pi

[BibTex]

[BibTex]


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Design and rolling locomotion of a magnetically actuated soft capsule endoscope

Yim, S., Sitti, M.

IEEE Transactions on Robotics, 28(1):183-194, IEEE, 2012 (article)

pi

Project Page [BibTex]

Project Page [BibTex]


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Design and manufacturing of a controllable miniature flapping wing robotic platform

Arabagi, V., Hines, L., Sitti, M.

The International Journal of Robotics Research, 31(6):785-800, SAGE Publications Sage UK: London, England, 2012 (article)

pi

[BibTex]

[BibTex]


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Chemotactic steering of bacteria propelled microbeads

Kim, D., Liu, A., Diller, E., Sitti, M.

Biomedical microdevices, 14(6):1009-1017, Springer US, 2012 (article)

pi

Project Page [BibTex]

Project Page [BibTex]


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Magnetic proximity effect in YBa2Cu3O7 / La2/3Ca1/3MnO3 and YBa2Cu3O7 / LaMnO3+δsuperlattices

Satapathy, D. K., Uribe-Laverde, M. A., Marozau, I., Malik, V. K., Das, S., Wagner, T., Marcelot, C., Stahn, J., Brück, S., Rühm, A., Macke, S., Tietze, T., Goering, E., Frañó, A., Kim, J., Wu, M., Benckiser, E., Keimer, B., Devishvili, A., Toperverg, B. P., Merz, M., Nagel, P., Schuppler, S., Bernhard, C.

{Physical Review Letters}, 108, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Noble gases and microporous frameworks; from interaction to application

Soleimani Dorcheh, A., Denysenko, D., Volkmer, D., Donner, W., Hirscher, M.

{Microporous and Mesoporous Materials}, 162, pages: 64-68, Elsevier, Amsterdam, 2012 (article)

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DOI [BibTex]

DOI [BibTex]


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Note: Unique characterization possibilities in the ultra high vacuum scanning transmission x-ray microscope (UHV-STXM) "MAXYMUS" using a rotatable permanent magnetic field up to 0.22 T

Nolle, D., Weigand, M., Audehm, P., Goering, E., Wiesemann, U., Wolter, C., Nolle, E., Schütz, G.

{Review of Scientific Instruments}, 83(4), 2012 (article)

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DOI [BibTex]


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Microstructure and superconducting properties of MgB2 films prepared by solid state reaction of multilayer precursors of the elements

Kugler, B., Stahl, C., Treiber, S., Soltan, S., Haug, S., Schütz, G., Albrecht, J.

{Thin Solid Films}, 520, pages: 6985-6988, 2012 (article)

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DOI [BibTex]

DOI [BibTex]

2008


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Modelling contrast discrimination data suggest both the pedestal effect and stochastic resonance to be caused by the same mechanism

Goris, R., Wagemans, J., Wichmann, F.

Journal of Vision, 8(15):1-21, November 2008 (article)

Abstract
Computational models of spatial vision typically make use of a (rectified) linear filter, a nonlinearity and dominant late noise to account for human contrast discrimination data. Linear–nonlinear cascade models predict an improvement in observers' contrast detection performance when low, subthreshold levels of external noise are added (i.e., stochastic resonance). Here, we address the issue whether a single contrast gain-control model of early spatial vision can account for both the pedestal effect, i.e., the improved detectability of a grating in the presence of a low-contrast masking grating, and stochastic resonance. We measured contrast discrimination performance without noise and in both weak and moderate levels of noise. Making use of a full quantitative description of our data with few parameters combined with comprehensive model selection assessments, we show the pedestal effect to be more reduced in the presence of weak noise than in moderate noise. This reduction rules out independent, additive sources of performance improvement and, together with a simulation study, supports the parsimonious explanation that a single mechanism underlies the pedestal effect and stochastic resonance in contrast perception.

ei

Web DOI [BibTex]


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gBoost: A Mathematical Programming Approach to Graph Classification and Regression

Saigo, H., Nowozin, S., Kadowaki, T., Kudo, T., Tsuda, K.

Machine Learning, 75(1):69-89, November 2008 (article)

Abstract
Graph mining methods enumerate frequently appearing subgraph patterns, which can be used as features for subsequent classification or regression. However, frequent patterns are not necessarily informative for the given learning problem. We propose a mathematical programming boosting method (gBoost) that progressively collects informative patterns. Compared to AdaBoost, gBoost can build the prediction rule with fewer iterations. To apply the boosting method to graph data, a branch-and-bound pattern search algorithm is developed based on the DFS code tree. The constructed search space is reused in later iterations to minimize the computation time. Our method can learn more efficiently than the simpler method based on frequent substructure mining, because the output labels are used as an extra information source for pruning the search space. Furthermore, by engineering the mathematical program, a wide range of machine learning problems can be solved without modifying the pattern search algorithm.

ei

PDF DOI [BibTex]

PDF DOI [BibTex]


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Variational Bayesian Model Selection in Linear Gaussian State-Space based Models

Chiappa, S.

International Workshop on Flexible Modelling: Smoothing and Robustness (FMSR 2008), 2008, pages: 1, November 2008 (poster)

ei

Web [BibTex]

Web [BibTex]


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Machine Learning for Motor Skills in Robotics

Peters, J.

K{\"u}nstliche Intelligenz, 2008(4):41-43, November 2008 (article)

Abstract
Autonomous robots that can adapt to novel situations has been a long standing vision of robotics, artificial intelligence, and the cognitive sciences. Early approaches to this goal during the heydays of artificial intelligence research in the late 1980s, however, made it clear that an approach purely based on reasoning or human insights would not be able to model all the perceptuomotor tasks of future robots. Instead, new hope was put in the growing wake of machine learning that promised fully adaptive control algorithms which learn both by observation and trial-and-error. However, to date, learning techniques have yet to fulfill this promise as only few methods manage to scale into the high-dimensional domains of manipulator and humanoid robotics and usually scaling was only achieved in precisely pre-structured domains. We have investigated the ingredients for a general approach to motor skill learning in order to get one step closer towards human-like performance. For doing so, we study two major components for such an approach, i.e., firstly, a theoretically well-founded general approach to representing the required control structures for task representation and execution and, secondly, appropriate learning algorithms which can be applied in this setting.

ei

PDF Web [BibTex]

PDF Web [BibTex]


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Kernels, Regularization and Differential Equations

Steinke, F., Schölkopf, B.

Pattern Recognition, 41(11):3271-3286, November 2008 (article)

Abstract
Many common machine learning methods such as Support Vector Machines or Gaussian process inference make use of positive definite kernels, reproducing kernel Hilbert spaces, Gaussian processes, and regularization operators. In this work these objects are presented in a general, unifying framework, and interrelations are highlighted. With this in mind we then show how linear stochastic differential equation models can be incorporated naturally into the kernel framework. And vice versa, many kernel machines can be interpreted in terms of differential equations. We focus especially on ordinary differential equations, also known as dynamical systems, and it is shown that standard kernel inference algorithms are equivalent to Kalman filter methods based on such models. In order not to cloud qualitative insights with heavy mathematical machinery, we restrict ourselves to finite domains, implying that differential equations are treated via their corresponding finite difference equations.

ei

PDF DOI [BibTex]

PDF DOI [BibTex]


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Mixture Models for Protein Structure Ensembles

Hirsch, M., Habeck, M.

Bioinformatics, 24(19):2184-2192, October 2008 (article)

ei

Web DOI [BibTex]

Web DOI [BibTex]


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Structure of the human voltage-dependent anion channel

Bayrhuber, M., Meins, T., Habeck, M., Becker, S., Giller, K., Villinger, S., Vonrhein, C., Griesinger, C., Zweckstetter, M., Zeth, K.

Proceedings of the National Academy of Sciences of the United States of America, 105(40):15370-15375, October 2008 (article)

Abstract
The voltage-dependent anion channel (VDAC), also known as mitochondrial porin, is the most abundant protein in the mitochondrial outer membrane (MOM). VDAC is the channel known to guide the metabolic flux across the MOM and plays a key role in mitochondrially induced apoptosis. Here, we present the 3D structure of human VDAC1, which was solved conjointly by NMR spectroscopy and x-ray crystallography. Human VDAC1 (hVDAC1) adopts a β-barrel architecture composed of 19 β-strands with an α-helix located horizontally midway within the pore. Bioinformatic analysis indicates that this channel architecture is common to all VDAC proteins and is adopted by the general import pore TOM40 of mammals, which is also located in the MOM.

ei

Web DOI [BibTex]

Web DOI [BibTex]


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MRI-Based Attenuation Correction for PET/MRI: A Novel Approach Combining Pattern Recognition and Atlas Registration

Hofmann, M., Steinke, F., Scheel, V., Charpiat, G., Farquhar, J., Aschoff, P., Brady, M., Schölkopf, B., Pichler, B.

Journal of Nuclear Medicine, 49(11):1875-1883, October 2008 (article)

Abstract
For quantitative PET information, correction of tissue photon attenuation is mandatory. Generally in conventional PET, the attenuation map is obtained from a transmission scan, which uses a rotating radionuclide source, or from the CT scan in a combined PET/CT scanner. In the case of PET/MRI scanners currently under development, insufficient space for the rotating source exists; the attenuation map can be calculated from the MR image instead. This task is challenging because MR intensities correlate with proton densities and tissue-relaxation properties, rather than with attenuation-related mass density. METHODS: We used a combination of local pattern recognition and atlas registration, which captures global variation of anatomy, to predict pseudo-CT images from a given MR image. These pseudo-CT images were then used for attenuation correction, as the process would be performed in a PET/CT scanner. RESULTS: For human brain scans, we show on a database of 17 MR/CT image pairs that our method reliably enables e stimation of a pseudo-CT image from the MR image alone. On additional datasets of MRI/PET/CT triplets of human brain scans, we compare MRI-based attenuation correction with CT-based correction. Our approach enables PET quantification with a mean error of 3.2% for predefined regions of interest, which we found to be clinically not significant. However, our method is not specific to brain imaging, and we show promising initial results on 1 whole-body animal dataset. CONCLUSION: This method allows reliable MRI-based attenuation correction for human brain scans. Further work is necessary to validate the method for whole-body imaging.

ei

Web DOI [BibTex]

Web DOI [BibTex]


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Support Vector Machines and Kernels for Computational Biology

Ben-Hur, A., Ong, C., Sonnenburg, S., Schölkopf, B., Rätsch, G.

PLoS Computational Biology, 4(10: e1000173):1-10, October 2008 (article)

ei

PDF Web DOI [BibTex]

PDF Web DOI [BibTex]


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Approximations for Binary Gaussian Process Classification

Nickisch, H., Rasmussen, C.

Journal of Machine Learning Research, 9, pages: 2035-2078, October 2008 (article)

Abstract
We provide a comprehensive overview of many recent algorithms for approximate inference in Gaussian process models for probabilistic binary classification. The relationships between several approaches are elucidated theoretically, and the properties of the different algorithms are corroborated by experimental results. We examine both 1) the quality of the predictive distributions and 2) the suitability of the different marginal likelihood approximations for model selection (selecting hyperparameters) and compare to a gold standard based on MCMC. Interestingly, some methods produce good predictive distributions although their marginal likelihood approximations are poor. Strong conclusions are drawn about the methods: The Expectation Propagation algorithm is almost always the method of choice unless the computational budget is very tight. We also extend existing methods in various ways, and provide unifying code implementing all approaches.

ei

PDF PDF [BibTex]

PDF PDF [BibTex]


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Accurate NMR Structures Through Minimization of an Extended Hybrid Energy

Nilges, M., Bernard, A., Bardiaux, B., Malliavin, T., Habeck, M., Rieping, W.

Structure, 16(9):1305-1312, September 2008 (article)

Abstract
The use of generous distance bounds has been the hallmark of NMR structure determination. However, bounds necessitate the estimation of data quality before the calculation, reduce the information content, introduce human bias, and allow for major errors in the structures. Here, we propose a new rapid structure calculation scheme based on Bayesian analysis. The minimization of an extended energy function, including a new type of distance restraint and a term depending on the data quality, results in an estimation of the data quality in addition to coordinates. This allows for the determination of the optimal weight on the experimental information. The resulting structures are of better quality and closer to the X–ray crystal structure of the same molecule. With the new calculation approach, the analysis of discrepancies from the target distances becomes meaningful. The strategy may be useful in other applications—for example, in homology modeling.

ei

PDF DOI [BibTex]

PDF DOI [BibTex]


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Similarity, Kernels, and the Triangle Inequality

Jäkel, F., Schölkopf, B., Wichmann, F.

Journal of Mathematical Psychology, 52(5):297-303, September 2008 (article)

Abstract
Similarity is used as an explanatory construct throughout psychology and multidimensional scaling (MDS) is the most popular way to assess similarity. In MDS, similarity is intimately connected to the idea of a geometric representation of stimuli in a perceptual space. Whilst connecting similarity and closeness of stimuli in a geometric representation may be intuitively plausible, Tversky and Gati [Tversky, A., Gati, I. (1982). Similarity, separability, and the triangle inequality. Psychological Review, 89(2), 123–154] have reported data which are inconsistent with the usual geometric representations that are based on segmental additivity. We show that similarity measures based on Shepard’s universal law of generalization [Shepard, R. N. (1987). Toward a universal law of generalization for psychologica science. Science, 237(4820), 1317–1323] lead to an inner product representation in a reproducing kernel Hilbert space. In such a space stimuli are represented by their similarity to all other stimuli. This representation, based on Shepard’s law, has a natural metric that does not have additive segments whilst still retaining the intuitive notion of connecting similarity and distance between stimuli. Furthermore, this representation has the psychologically appealing property that the distance between stimuli is bounded.

ei

PDF Web DOI [BibTex]

PDF Web DOI [BibTex]


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Comparison of Pattern Recognition Methods in Classifying High-resolution BOLD Signals Obtained at High Magnetic Field in Monkeys

Ku, S., Gretton, A., Macke, J., Logothetis, N.

Magnetic Resonance Imaging, 26(7):1007-1014, September 2008 (article)

Abstract
Pattern recognition methods have shown that functional magnetic resonance imaging (fMRI) data can reveal significant information about brain activity. For example, in the debate of how object categories are represented in the brain, multivariate analysis has been used to provide evidence of a distributed encoding scheme [Science 293:5539 (2001) 2425–2430]. Many follow-up studies have employed different methods to analyze human fMRI data with varying degrees of success [Nature reviews 7:7 (2006) 523–534]. In this study, we compare four popular pattern recognition methods: correlation analysis, support-vector machines (SVM), linear discriminant analysis (LDA) and Gaussian naïve Bayes (GNB), using data collected at high field (7 Tesla) with higher resolution than usual fMRI studies. We investigate prediction performance on single trials and for averages across varying numbers of stimulus presentations. The performance of the various algorithms depends on the nature of the brain activity being categorized: for several tasks, many of the methods work well, whereas for others, no method performs above chance level. An important factor in overall classification performance is careful preprocessing of the data, including dimensionality reduction, voxel selection and outlier elimination.

ei

PDF Web DOI [BibTex]

PDF Web DOI [BibTex]


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Towards the neural basis of the flash-lag effect

Ecker, A., Berens, P., Hoenselaar, A., Subramaniyan, M., Tolias, A., Bethge, M.

International Workshop on Aspects of Adaptive Cortex Dynamics, 2008, pages: 1, September 2008 (poster)

ei

PDF [BibTex]

PDF [BibTex]


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A Single-shot Measurement of the Energy of Product States in a Translation Invariant Spin Chain Can Replace Any Quantum Computation

Janzing, D., Wocjan, P., Zhang, S.

New Journal of Physics, 10(093004):1-18, September 2008 (article)

Abstract
In measurement-based quantum computation, quantum algorithms are implemented via sequences of measurements. We describe a translationally invariant finite-range interaction on a one-dimensional qudit chain and prove that a single-shot measurement of the energy of an appropriate computational basis state with respect to this Hamiltonian provides the output of any quantum circuit. The required measurement accuracy scales inverse polynomially with the size of the simulated quantum circuit. This shows that the implementation of energy measurements on generic qudit chains is as hard as the realization of quantum computation. Here, a ‘measurement‘ is any procedure that samples from the spectral measurement induced by the observable and the state under consideration. As opposed to measurement-based quantum computation, the post-measurement state is irrelevant.

ei

PDF DOI [BibTex]


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Voluntary Brain Regulation and Communication with ECoG-Signals

Hinterberger, T., Widmann, G., Lal, T., Hill, J., Tangermann, M., Rosenstiel, W., Schölkopf, B., Elger, C., Birbaumer, N.

Epilepsy and Behavior, 13(2):300-306, August 2008 (article)

Abstract
Brain–computer interfaces (BCIs) can be used for communication in writing without muscular activity or for learning to control seizures by voluntary regulation of brain signals such as the electroencephalogram (EEG). Three of five patients with epilepsy were able to spell their names with electrocorticogram (ECoG) signals derived from motor-related areas within only one or two training sessions. Imagery of finger or tongue movements was classified with support-vector classification of autoregressive coefficients derived from the ECoG signals. After training of the classifier, binary classification responses were used to select letters from a computer-generated menu. Offline analysis showed increased theta activity in the unsuccessful patients, whereas the successful patients exhibited dominant sensorimotor rhythms that they could control. The high spatial resolution and increased signal-to-noise ratio in ECoG signals, combined with short training periods, may offer an alternative for communication in complete paralysis, locked-in syndrome, and motor restoration.

ei

PDF DOI [BibTex]

PDF DOI [BibTex]


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Multi-class Common Spatial Pattern and Information Theoretic Feature Extraction

Grosse-Wentrup, M., Buss, M.

IEEE Transactions on Biomedical Engineering, 55(8):1991-2000, August 2008 (article)

Abstract
We address two shortcomings of the common spatial patterns (CSP) algorithm for spatial filtering in the context of brain--computer interfaces (BCIs) based on electroencephalography/magnetoencephalography (EEG/MEG): First, the question of optimality of CSP in terms of the minimal achievable classification error remains unsolved. Second, CSP has been initially proposed for two-class paradigms. Extensions to multiclass paradigms have been suggested, but are based on heuristics. We address these shortcomings in the framework of information theoretic feature extraction (ITFE). We show that for two-class paradigms, CSP maximizes an approximation of mutual information of extracted EEG/MEG components and class labels. This establishes a link between CSP and the minimal classification error. For multiclass paradigms, we point out that CSP by joint approximate diagonalization (JAD) is equivalent to independent component analysis (ICA), and provide a method to choose those independent components (ICs) that approximately maximize mutual information of ICs and class labels. This eliminates the need for heuristics in multiclass CSP, and allows incorporating prior class probabilities. The proposed method is applied to the dataset IIIa of the third BCI competition, and is shown to increase the mean classification accuracy by 23.4% in comparison to multiclass CSP.

ei

PDF Web DOI [BibTex]

PDF Web DOI [BibTex]


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Policy Learning: A Unified Perspective With Applications In Robotics

Peters, J., Kober, J., Nguyen-Tuong, D.

8th European Workshop on Reinforcement Learning for Robotics (EWRL 2008), 8, pages: 10, July 2008 (poster)

Abstract
Policy Learning approaches are among the best suited methods for high-dimensional, continuous control systems such as anthropomorphic robot arms and humanoid robots. In this paper, we show two contributions: firstly, we show a unified perspective which allows us to derive several policy learning al- gorithms from a common point of view, i.e, policy gradient algorithms, natural- gradient algorithms and EM-like policy learning. Secondly, we present several applications to both robot motor primitive learning as well as to robot control in task space. Results both from simulation and several different real robots are shown.

ei

PDF [BibTex]

PDF [BibTex]


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At-TAX: A Whole Genome Tiling Array Resource for Developmental Expression Analysis and Transcript Identification in Arabidopsis thaliana

Laubinger, S., Zeller, G., Henz, S., Sachsenberg, T., Widmer, C., Naouar, N., Vuylsteke, M., Schölkopf, B., Rätsch, G., Weigel, D.

Genome Biology, 9(7: R112):1-16, July 2008 (article)

Abstract
Gene expression maps for model organisms, including Arabidopsis thaliana, have typically been created using gene-centric expression arrays. Here, we describe a comprehensive expression atlas, Arabidopsis thaliana Tiling Array Express (At-TAX), which is based on whole-genome tiling arrays. We demonstrate that tiling arrays are accurate tools for gene expression analysis and identified more than 1,000 unannotated transcribed regions. Visualizations of gene expression estimates, transcribed regions, and tiling probe measurements are accessible online at the At-TAX homepage.

ei

PDF DOI [BibTex]

PDF DOI [BibTex]