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Adaptive nonparametric detection in cryo-electron microscopy


Conference Paper


We develop a novel method for detection of signals and reconstruction of images in the presence of random noise. The method uses results from percolation theory. We specifically address the problem of detection of multiple objects of unknown shapes in the case of nonparametric noise. The noise density is unknown and can be heavy-tailed. The objects of interest have unknown varying intensities. No boundary shape constraints are imposed on the objects, only a set of weak bulk conditions is required. We view the object detection problem as hypothesis testing for discrete statistical inverse problems. We present an algorithm that allows to detect greyscale objects of various shapes in noisy images. We prove results on consistency and algorithmic complexity of our procedures. Applications to cryo-electron microscopy are presented.

Author(s): Langovoy, M. and Habeck, M. and Schölkopf, B.
Book Title: Proceedings of the 58th World Statistics Congress
Pages: 4456--4461
Year: 2011
Month: August
Day: 0

Department(s): Empirical Inference
Bibtex Type: Conference Paper (inproceedings)

Event Name: ISI 2011
Event Place: Dublin, Ireland

URL: http://2011.isiproceedings.org/papers/950982.pdf

Links: PDF


  title = {Adaptive nonparametric detection in cryo-electron microscopy},
  author = {Langovoy, M. and Habeck, M. and Sch{\"o}lkopf, B.},
  booktitle = {Proceedings of the 58th World Statistics Congress},
  pages = {4456--4461},
  month = aug,
  year = {2011},
  url = {http://2011.isiproceedings.org/papers/950982.pdf},
  month_numeric = {8}