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2017


Probabilistic Line Searches for Stochastic Optimization
Probabilistic Line Searches for Stochastic Optimization

Mahsereci, M., Hennig, P.

Journal of Machine Learning Research, 18(119):1-59, November 2017 (article)

pn

link (url) Project Page [BibTex]

2017


link (url) Project Page [BibTex]


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Generalized exploration in policy search

van Hoof, H., Tanneberg, D., Peters, J.

Machine Learning, 106(9-10):1705-1724 , (Editors: Kurt Driessens, Dragi Kocev, Marko Robnik‐Sikonja, and Myra Spiliopoulou), October 2017, Special Issue of the ECML PKDD 2017 Journal Track (article)

ei

DOI Project Page [BibTex]

DOI Project Page [BibTex]


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Probabilistic Prioritization of Movement Primitives

Paraschos, A., Lioutikov, R., Peters, J., Neumann, G.

Proceedings of the International Conference on Intelligent Robot Systems, and IEEE Robotics and Automation Letters (RA-L), 2(4):2294-2301, October 2017 (article)

ei

link (url) DOI [BibTex]

link (url) DOI [BibTex]


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Learning Movement Primitive Libraries through Probabilistic Segmentation

Lioutikov, R., Neumann, G., Maeda, G., Peters, J.

International Journal of Robotics Research, 36(8):879-894, July 2017 (article)

ei

DOI Project Page [BibTex]

DOI Project Page [BibTex]


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Guiding Trajectory Optimization by Demonstrated Distributions

Osa, T., Ghalamzan E., A. M., Stolkin, R., Lioutikov, R., Peters, J., Neumann, G.

IEEE Robotics and Automation Letters, 2(2):819-826, April 2017 (article)

ei

DOI [BibTex]

DOI [BibTex]


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Whole-body multi-contact motion in humans and humanoids: Advances of the CoDyCo European project

Padois, V., Ivaldi, S., Babic, J., Mistry, M., Peters, J., Nori, F.

Robotics and Autonomous Systems, 90, pages: 97-117, April 2017, Special Issue on New Research Frontiers for Intelligent Autonomous Systems (article)

ei

DOI Project Page [BibTex]

DOI Project Page [BibTex]


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Probabilistic Movement Primitives for Coordination of Multiple Human-Robot Collaborative Tasks

Maeda, G., Neumann, G., Ewerton, M., Lioutikov, R., Kroemer, O., Peters, J.

Autonomous Robots, 41(3):593-612, March 2017 (article)

ei

DOI Project Page [BibTex]

DOI Project Page [BibTex]


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Bioinspired tactile sensor for surface roughness discrimination

Yi, Z., Zhang, Y., Peters, J.

Sensors and Actuators A: Physical, 255, pages: 46-53, March 2017 (article)

ei

DOI Project Page [BibTex]

DOI Project Page [BibTex]


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Model-based Contextual Policy Search for Data-Efficient Generalization of Robot Skills

Kupcsik, A., Deisenroth, M., Peters, J., Ai Poh, L., Vadakkepat, V., Neumann, G.

Artificial Intelligence, 247, pages: 415-439, 2017, Special Issue on AI and Robotics (article)

ei

link (url) DOI Project Page [BibTex]

link (url) DOI Project Page [BibTex]


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Anticipatory Action Selection for Human-Robot Table Tennis

Wang, Z., Boularias, A., Mülling, K., Schölkopf, B., Peters, J.

Artificial Intelligence, 247, pages: 399-414, 2017, Special Issue on AI and Robotics (article)

Abstract
Abstract Anticipation can enhance the capability of a robot in its interaction with humans, where the robot predicts the humans' intention for selecting its own action. We present a novel framework of anticipatory action selection for human-robot interaction, which is capable to handle nonlinear and stochastic human behaviors such as table tennis strokes and allows the robot to choose the optimal action based on prediction of the human partner's intention with uncertainty. The presented framework is generic and can be used in many human-robot interaction scenarios, for example, in navigation and human-robot co-manipulation. In this article, we conduct a case study on human-robot table tennis. Due to the limited amount of time for executing hitting movements, a robot usually needs to initiate its hitting movement before the opponent hits the ball, which requires the robot to be anticipatory based on visual observation of the opponent's movement. Previous work on Intention-Driven Dynamics Models (IDDM) allowed the robot to predict the intended target of the opponent. In this article, we address the problem of action selection and optimal timing for initiating a chosen action by formulating the anticipatory action selection as a Partially Observable Markov Decision Process (POMDP), where the transition and observation are modeled by the \{IDDM\} framework. We present two approaches to anticipatory action selection based on the \{POMDP\} formulation, i.e., a model-free policy learning method based on Least-Squares Policy Iteration (LSPI) that employs the \{IDDM\} for belief updates, and a model-based Monte-Carlo Planning (MCP) method, which benefits from the transition and observation model by the IDDM. Experimental results using real data in a simulated environment show the importance of anticipatory action selection, and that \{POMDPs\} are suitable to formulate the anticipatory action selection problem by taking into account the uncertainties in prediction. We also show that existing algorithms for POMDPs, such as \{LSPI\} and MCP, can be applied to substantially improve the robot's performance in its interaction with humans.

am ei

DOI Project Page [BibTex]

DOI Project Page [BibTex]


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easyGWAS: A Cloud-based Platform for Comparing the Results of Genome-wide Association Studies

Grimm, D., Roqueiro, D., Salome, P., Kleeberger, S., Greshake, B., Zhu, W., Liu, C., Lippert, C., Stegle, O., Schölkopf, B., Weigel, D., Borgwardt, K.

The Plant Cell, 29(1):5-19, 2017 (article)

ei

link (url) DOI [BibTex]

link (url) DOI [BibTex]


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A Novel Unsupervised Segmentation Approach Quantifies Tumor Tissue Populations Using Multiparametric MRI: First Results with Histological Validation

Katiyar, P., Divine, M. R., Kohlhofer, U., Quintanilla-Martinez, L., Schölkopf, B., Pichler, B. J., Disselhorst, J. A.

Molecular Imaging and Biology, 19(3):391-397, 2017 (article)

ei

DOI [BibTex]

DOI [BibTex]


Early Stopping Without a Validation Set
Early Stopping Without a Validation Set

Mahsereci, M., Balles, L., Lassner, C., Hennig, P.

arXiv preprint arXiv:1703.09580, 2017 (article)

Abstract
Early stopping is a widely used technique to prevent poor generalization performance when training an over-expressive model by means of gradient-based optimization. To find a good point to halt the optimizer, a common practice is to split the dataset into a training and a smaller validation set to obtain an ongoing estimate of the generalization performance. In this paper we propose a novel early stopping criterion which is based on fast-to-compute, local statistics of the computed gradients and entirely removes the need for a held-out validation set. Our experiments show that this is a viable approach in the setting of least-squares and logistic regression as well as neural networks.

ps pn

link (url) Project Page Project Page [BibTex]


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Krylov Subspace Recycling for Fast Iterative Least-Squares in Machine Learning

Roos, F. D., Hennig, P.

arXiv preprint arXiv:1706.00241, 2017 (article)

Abstract
Solving symmetric positive definite linear problems is a fundamental computational task in machine learning. The exact solution, famously, is cubicly expensive in the size of the matrix. To alleviate this problem, several linear-time approximations, such as spectral and inducing-point methods, have been suggested and are now in wide use. These are low-rank approximations that choose the low-rank space a priori and do not refine it over time. While this allows linear cost in the data-set size, it also causes a finite, uncorrected approximation error. Authors from numerical linear algebra have explored ways to iteratively refine such low-rank approximations, at a cost of a small number of matrix-vector multiplications. This idea is particularly interesting in the many situations in machine learning where one has to solve a sequence of related symmetric positive definite linear problems. From the machine learning perspective, such deflation methods can be interpreted as transfer learning of a low-rank approximation across a time-series of numerical tasks. We study the use of such methods for our field. Our empirical results show that, on regression and classification problems of intermediate size, this approach can interpolate between low computational cost and numerical precision.

pn

link (url) Project Page [BibTex]


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Minimax Estimation of Kernel Mean Embeddings

Tolstikhin, I., Sriperumbudur, B., Muandet, K.

Journal of Machine Learning Research, 18(86):1-47, 2017 (article)

ei

link (url) Project Page [BibTex]


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Kernel Mean Embedding of Distributions: A Review and Beyond

Muandet, K., Fukumizu, K., Sriperumbudur, B., Schölkopf, B.

Foundations and Trends in Machine Learning, 10(1-2):1-141, 2017 (article)

ei

DOI Project Page [BibTex]

DOI Project Page [BibTex]


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Convergence Analysis of Deterministic Kernel-Based Quadrature Rules in Misspecified Settings

Kanagawa, M., Sriperumbudur, B. K., Fukumizu, K.

Arxiv e-prints, arXiv:1709.00147v1 [math.NA], 2017 (article)

Abstract
This paper presents convergence analysis of kernel-based quadrature rules in misspecified settings, focusing on deterministic quadrature in Sobolev spaces. In particular, we deal with misspecified settings where a test integrand is less smooth than a Sobolev RKHS based on which a quadrature rule is constructed. We provide convergence guarantees based on two different assumptions on a quadrature rule: one on quadrature weights, and the other on design points. More precisely, we show that convergence rates can be derived (i) if the sum of absolute weights remains constant (or does not increase quickly), or (ii) if the minimum distance between distance design points does not decrease very quickly. As a consequence of the latter result, we derive a rate of convergence for Bayesian quadrature in misspecified settings. We reveal a condition on design points to make Bayesian quadrature robust to misspecification, and show that, under this condition, it may adaptively achieve the optimal rate of convergence in the Sobolev space of a lesser order (i.e., of the unknown smoothness of a test integrand), under a slightly stronger regularity condition on the integrand.

pn

arXiv [BibTex]

arXiv [BibTex]


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Prediction of intention during interaction with iCub with Probabilistic Movement Primitives

Dermy, O., Paraschos, A., Ewerton, M., Charpillet, F., Peters, J., Ivaldi, S.

Frontiers in Robotics and AI, 4, pages: 45, 2017 (article)

ei

DOI Project Page [BibTex]

DOI Project Page [BibTex]


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Manifold-based multi-objective policy search with sample reuse

Parisi, S., Pirotta, M., Peters, J.

Neurocomputing, 263, pages: 3-14, (Editors: Madalina Drugan, Marco Wiering, Peter Vamplew, and Madhu Chetty), 2017, Special Issue on Multi-Objective Reinforcement Learning (article)

ei

DOI Project Page [BibTex]

DOI Project Page [BibTex]


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Spectral Clustering predicts tumor tissue heterogeneity using dynamic 18F-FDG PET: a complement to the standard compartmental modeling approach

Katiyar, P., Divine, M. R., Kohlhofer, U., Quintanilla-Martinez, L., Schölkopf, B., Pichler, B. J., Disselhorst, J. A.

Journal of Nuclear Medicine, 58(4):651-657, 2017 (article)

ei

link (url) DOI [BibTex]

link (url) DOI [BibTex]


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Electroencephalographic identifiers of motor adaptation learning

Ozdenizci, O., Yalcin, M., Erdogan, A., Patoglu, V., Grosse-Wentrup, M., Cetin, M.

Journal of Neural Engineering, 14(4):046027, 2017 (article)

ei

link (url) [BibTex]

link (url) [BibTex]


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Detecting distortions of peripherally presented letter stimuli under crowded conditions

Wallis, T. S. A., Tobias, S., Bethge, M., Wichmann, F. A.

Attention, Perception, & Psychophysics, 79(3):850-862, 2017 (article)

ei

DOI Project Page [BibTex]

DOI Project Page [BibTex]


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Temporal evolution of the central fixation bias in scene viewing

Rothkegel, L. O. M., Trukenbrod, H. A., Schütt, H. H., Wichmann, F. A., Engbert, R.

Journal of Vision, 17(13):3, 2017 (article)

ei

DOI Project Page [BibTex]

DOI Project Page [BibTex]


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BundleMAP: Anatomically Localized Classification, Regression, and Hypothesis Testing in Diffusion MRI

Khatami, M., Schmidt-Wilcke, T., Sundgren, P. C., Abbasloo, A., Schölkopf, B., Schultz, T.

Pattern Recognition, 63, pages: 593-600, 2017 (article)

ei

DOI [BibTex]

DOI [BibTex]


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A parametric texture model based on deep convolutional features closely matches texture appearance for humans

Wallis, T. S. A., Funke, C. M., Ecker, A. S., Gatys, L. A., Wichmann, F. A., Bethge, M.

Journal of Vision, 17(12), 2017 (article)

ei

DOI Project Page [BibTex]

DOI Project Page [BibTex]


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Model Selection for Gaussian Mixture Models

Huang, T., Peng, H., Zhang, K.

Statistica Sinica, 27(1):147-169, 2017 (article)

ei

link (url) [BibTex]

link (url) [BibTex]


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An image-computable psychophysical spatial vision model

Schütt, H. H., Wichmann, F. A.

Journal of Vision, 17(12), 2017 (article)

ei

DOI Project Page [BibTex]

DOI Project Page [BibTex]


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Methods and measurements to compare men against machines

Wichmann, F. A., Janssen, D. H. J., Geirhos, R., Aguilar, G., Schütt, H. H., Maertens, M., Bethge, M.

Electronic Imaging, pages: 36-45(10), 2017 (article)

ei

DOI [BibTex]

DOI [BibTex]


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A Comparison of Autoregressive Hidden Markov Models for Multimodal Manipulations With Variable Masses

Kroemer, O., Peters, J.

IEEE Robotics and Automation Letters, 2(2):1101-1108, 2017 (article)

ei

DOI [BibTex]

DOI [BibTex]


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Phase Estimation for Fast Action Recognition and Trajectory Generation in Human-Robot Collaboration

Maeda, G., Ewerton, M., Neumann, G., Lioutikov, R., Peters, J.

International Journal of Robotics Research, 36(13-14):1579-1594, 2017, Special Issue on the Seventeenth International Symposium on Robotics Research (article)

ei

DOI Project Page [BibTex]

DOI Project Page [BibTex]


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A Phase-coded Aperture Camera with Programmable Optics

Chen, J., Hirsch, M., Heintzmann, R., Eberhardt, B., Lensch, H. P. A.

Electronic Imaging, 2017(17):70-75, 2017 (article)

ei

DOI [BibTex]

DOI [BibTex]


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Efficiency of analytical and sampling-based uncertainty propagation in intensity-modulated proton therapy

Wahl, N., Hennig, P., Wieser, H. P., Bangert, M.

Physics in Medicine & Biology, 62(14):5790-5807, 2017 (article)

Abstract
The sensitivity of intensity-modulated proton therapy (IMPT) treatment plans to uncertainties can be quantified and mitigated with robust/min-max and stochastic/probabilistic treatment analysis and optimization techniques. Those methods usually rely on sparse random, importance, or worst-case sampling. Inevitably, this imposes a trade-off between computational speed and accuracy of the uncertainty propagation. Here, we investigate analytical probabilistic modeling (APM) as an alternative for uncertainty propagation and minimization in IMPT that does not rely on scenario sampling. APM propagates probability distributions over range and setup uncertainties via a Gaussian pencil-beam approximation into moments of the probability distributions over the resulting dose in closed form. It supports arbitrary correlation models and allows for efficient incorporation of fractionation effects regarding random and systematic errors. We evaluate the trade-off between run-time and accuracy of APM uncertainty computations on three patient datasets. Results are compared against reference computations facilitating importance and random sampling. Two approximation techniques to accelerate uncertainty propagation and minimization based on probabilistic treatment plan optimization are presented. Runtimes are measured on CPU and GPU platforms, dosimetric accuracy is quantified in comparison to a sampling-based benchmark (5000 random samples). APM accurately propagates range and setup uncertainties into dose uncertainties at competitive run-times (GPU ##IMG## [http://ej.iop.org/images/0031-9155/62/14/5790/pmbaa6ec5ieqn001.gif] {$\leqslant {5}$} min). The resulting standard deviation (expectation value) of dose show average global ##IMG## [http://ej.iop.org/images/0031-9155/62/14/5790/pmbaa6ec5ieqn002.gif] {$\gamma_{{3}\% / {3}~{\rm mm}}$} pass rates between 94.2% and 99.9% (98.4% and 100.0%). All investigated importance sampling strategies provided less accuracy at higher run-times considering only a single fraction. Considering fractionation, APM uncertainty propagation and treatment plan optimization was proven to be possible at constant time complexity, while run-times of sampling-based computations are linear in the number of fractions. Using sum sampling within APM, uncertainty propagation can only be accelerated at the cost of reduced accuracy in variance calculations. For probabilistic plan optimization, we were able to approximate the necessary pre-computations within seconds, yielding treatment plans of similar quality as gained from exact uncertainty propagation. APM is suited to enhance the trade-off between speed and accuracy in uncertainty propagation and probabilistic treatment plan optimization, especially in the context of fractionation. This brings fully-fledged APM computations within reach of clinical application.

pn

link (url) [BibTex]

link (url) [BibTex]


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Analytical probabilistic modeling of RBE-weighted dose for ion therapy

Wieser, H., Hennig, P., Wahl, N., Bangert, M.

Physics in Medicine and Biology (PMB), 62(23):8959-8982, 2017 (article)

pn

link (url) [BibTex]

link (url) [BibTex]


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On Maximum Entropy and Inference

Gresele, L., Marsili, M.

Entropy, 19(12):article no. 642, 2017 (article)

ei

link (url) [BibTex]

link (url) [BibTex]


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Towards Engagement Models that Consider Individual Factors in HRI: On the Relation of Extroversion and Negative Attitude Towards Robots to Gaze and Speech During a Human-Robot Assembly Task

Ivaldi, S., Lefort, S., Peters, J., Chetouani, M., Provasi, J., Zibetti, E.

International Journal of Social Robotics, 9(1):63-86, 2017 (article)

ei

DOI [BibTex]

DOI [BibTex]


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Non-parametric Policy Search with Limited Information Loss

van Hoof, H., Neumann, G., Peters, J.

Journal of Machine Learning Research , 18(73):1-46, 2017 (article)

ei

link (url) Project Page [BibTex]

link (url) Project Page [BibTex]


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Stability of Controllers for Gaussian Process Dynamics

Vinogradska, J., Bischoff, B., Nguyen-Tuong, D., Peters, J.

Journal of Machine Learning Research, 18(100):1-37, 2017 (article)

ei

link (url) Project Page [BibTex]

link (url) Project Page [BibTex]


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SUV-quantification of physiological lung tissue in an integrated PET/MR-system: Impact of lung density and bone tissue

Seith, F., Schmidt, H., Gatidis, S., Bezrukov, I., Schraml, C., Pfannenberg, C., la Fougère, C., Nikolaou, K., Schwenzer, N.

PLOS ONE, 12(5):1-13, 2017 (article)

ei

DOI [BibTex]

DOI [BibTex]

2004


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On the representation, learning and transfer of spatio-temporal movement characteristics

Ilg, W., Bakir, GH., Mezger, J., Giese, M.

International Journal of Humanoid Robotics, 1(4):613-636, December 2004 (article)

ei

[BibTex]

2004


[BibTex]


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Insect-inspired estimation of egomotion

Franz, MO., Chahl, JS., Krapp, HG.

Neural Computation, 16(11):2245-2260, November 2004 (article)

Abstract
Tangential neurons in the fly brain are sensitive to the typical optic flow patterns generated during egomotion. In this study, we examine whether a simplified linear model based on the organization principles in tangential neurons can be used to estimate egomotion from the optic flow. We present a theory for the construction of an estimator consisting of a linear combination of optic flow vectors that incorporates prior knowledge both about the distance distribution of the environment, and about the noise and egomotion statistics of the sensor. The estimator is tested on a gantry carrying an omnidirectional vision sensor. The experiments show that the proposed approach leads to accurate and robust estimates of rotation rates, whereas translation estimates are of reasonable quality, albeit less reliable.

ei

PDF PostScript Web DOI [BibTex]

PDF PostScript Web DOI [BibTex]


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Efficient face detection by a cascaded support-vector machine expansion

Romdhani, S., Torr, P., Schölkopf, B., Blake, A.

Proceedings of The Royal Society of London A, 460(2501):3283-3297, A, November 2004 (article)

Abstract
We describe a fast system for the detection and localization of human faces in images using a nonlinear ‘support-vector machine‘. We approximate the decision surface in terms of a reduced set of expansion vectors and propose a cascaded evaluation which has the property that the full support-vector expansion is only evaluated on the face-like parts of the image, while the largest part of typical images is classified using a single expansion vector (a simpler and more efficient classifier). As a result, only three reduced-set vectors are used, on average, to classify an image patch. Hence, the cascaded evaluation, presented in this paper, offers a thirtyfold speed-up over an evaluation using the full set of reduced-set vectors, which is itself already thirty times faster than classification using all the support vectors.

ei

PDF DOI [BibTex]

PDF DOI [BibTex]


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Learning kernels from biological networks by maximizing entropy

Tsuda, K., Noble, W.

Bioinformatics, 20(Suppl. 1):i326-i333, August 2004 (article)

Abstract
Motivation: The diffusion kernel is a general method for computing pairwise distances among all nodes in a graph, based on the sum of weighted paths between each pair of nodes. This technique has been used successfully, in conjunction with kernel-based learning methods, to draw inferences from several types of biological networks. Results: We show that computing the diffusion kernel is equivalent to maximizing the von Neumann entropy, subject to a global constraint on the sum of the Euclidean distances between nodes. This global constraint allows for high variance in the pairwise distances. Accordingly, we propose an alternative, locally constrained diffusion kernel, and we demonstrate that the resulting kernel allows for more accurate support vector machine prediction of protein functional classifications from metabolic and protein–protein interaction networks.

ei

PDF Web [BibTex]

PDF Web [BibTex]


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Masking effect produced by Mach bands on the detection of narrow bars of random polarity

Henning, GB., Hoddinott, KT., Wilson-Smith, ZJ., Hill, NJ.

Journal of the Optical Society of America, 21(8):1379-1387, A, August 2004 (article)

ei

[BibTex]

[BibTex]


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Support Vector Channel Selection in BCI

Lal, T., Schröder, M., Hinterberger, T., Weston, J., Bogdan, M., Birbaumer, N., Schölkopf, B.

IEEE Transactions on Biomedical Engineering, 51(6):1003-1010, June 2004 (article)

Abstract
Designing a Brain Computer Interface (BCI) system one can choose from a variety of features that may be useful for classifying brain activity during a mental task. For the special case of classifying EEG signals we propose the usage of the state of the art feature selection algorithms Recursive Feature Elimination and Zero-Norm Optimization which are based on the training of Support Vector Machines (SVM). These algorithms can provide more accurate solutions than standard filter methods for feature selection. We adapt the methods for the purpose of selecting EEG channels. For a motor imagery paradigm we show that the number of used channels can be reduced significantly without increasing the classification error. The resulting best channels agree well with the expected underlying cortical activity patterns during the mental tasks. Furthermore we show how time dependent task specific information can be visualized.

ei

DOI [BibTex]

DOI [BibTex]


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Distance-Based Classification with Lipschitz Functions

von Luxburg, U., Bousquet, O.

Journal of Machine Learning Research, 5, pages: 669-695, June 2004 (article)

Abstract
The goal of this article is to develop a framework for large margin classification in metric spaces. We want to find a generalization of linear decision functions for metric spaces and define a corresponding notion of margin such that the decision function separates the training points with a large margin. It will turn out that using Lipschitz functions as decision functions, the inverse of the Lipschitz constant can be interpreted as the size of a margin. In order to construct a clean mathematical setup we isometrically embed the given metric space into a Banach space and the space of Lipschitz functions into its dual space. To analyze the resulting algorithm, we prove several representer theorems. They state that there always exist solutions of the Lipschitz classifier which can be expressed in terms of distance functions to training points. We provide generalization bounds for Lipschitz classifiers in terms of the Rademacher complexities of some Lipschitz function classes. The generality of our approach can be seen from the fact that several well-known algorithms are special cases of the Lipschitz classifier, among them the support vector machine, the linear programming machine, and the 1-nearest neighbor classifier.

ei

PDF PostScript PDF [BibTex]

PDF PostScript PDF [BibTex]


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cDNA-Microarray Technology in Cartilage Research - Functional Genomics of Osteoarthritis [in German]

Aigner, T., Finger, F., Zien, A., Bartnik, E.

Zeitschrift f{\"u}r Orthop{\"a}die und ihre Grenzgebiete, 142(2):241-247, April 2004 (article)

Abstract
Functional genomics represents a new challenging approach in order to analyze complex diseases such as osteoarthritis on a molecular level. The characterization of the molecular changes of the cartilage cells, the chondrocytes, enables a better understanding of the pathomechanisms of the disease. In particular, the identification and characterization of new target molecules for therapeutic intervention is of interest. Also, potential molecular markers for diagnosis and monitoring of osteoarthritis contribute to a more appropriate patient management. The DNA-microarray technology complements (but does not replace) biochemical and biological research in new disease-relevant genes. Large-scale functional genomics will identify molecular networks such as yet identified players in the anabolic-catabolic balance of articular cartilage as well as disease-relevant intracellular signaling cascades so far rather unknown in articular chondrocytes. However, at the moment it is also important to recognize the limitations of the microarray technology in order to avoid over-interpretation of the results. This might lead to misleading results and prevent to a significant extent a proper use of the potential of this technology in the field of osteoarthritis.

ei

[BibTex]

[BibTex]