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2004


On the variability of manual spike sorting
On the variability of manual spike sorting

Wood, F., Black, M. J., Vargas-Irwin, C., Fellows, M., Donoghue, J. P.

IEEE Trans. Biomedical Engineering, 51(6):912-918, June 2004 (article)

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pdf pdf from publisher [BibTex]

2004


pdf pdf from publisher [BibTex]


Modeling and decoding motor cortical activity using a switching {Kalman} filter
Modeling and decoding motor cortical activity using a switching Kalman filter

Wu, W., Black, M. J., Mumford, D., Gao, Y., Bienenstock, E., Donoghue, J. P.

IEEE Trans. Biomedical Engineering, 51(6):933-942, June 2004 (article)

Abstract
We present a switching Kalman filter model for the real-time inference of hand kinematics from a population of motor cortical neurons. Firing rates are modeled as a Gaussian mixture where the mean of each Gaussian component is a linear function of hand kinematics. A “hidden state” models the probability of each mixture component and evolves over time in a Markov chain. The model generalizes previous encoding and decoding methods, addresses the non-Gaussian nature of firing rates, and can cope with crudely sorted neural data common in on-line prosthetic applications.

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pdf pdf from publisher [BibTex]

pdf pdf from publisher [BibTex]


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E. Coli Inspired Propulsion for Swimming Microrobots

Behkam, Bahareh, Sitti, Metin

pages: 1037–1041, 2004 (article)

Abstract
Medical applications are among the most fascinating areas of microrobotics. For long, scientists have dreamed of miniature smart devices that can travel inside the human body and carry out a host of complex operations such as minimally invasive surgery (MIS), highly localized drug delivery, and screening for diseases that are in their very early stages. Still a distant dream, significant progress in micro and nanotechnology brings us closer to materializing it. For such a miniature device to be injected into the body, it has to be 800 μm or smaller in diameter. Miniature, safe and energy efficient propulsion systems hold the key to maturing this technology but they pose significant challenges. Scaling the macroscale natation mechanisms to micro/nano length scales is unfeasible. It has been estimated that a vibrating-fin driven swimming robot shorter than 6 mm can not overcome the viscous drag forces in water. In this paper, the authors propose a new type of propulsion inspired by the motility mechanism of bacteria with peritrichous flagellation, such as Escherichia coli, Salmonella typhimurium and Serratia marcescens. The perfomance of the propulsive mechanism is estimated by modeling the dynamics of the motion. The motion of the moving organelle is simulated and key parameters such as velocity, distribution of force and power requirments for different configurations of the tail are determined theoretically. In order to validate the theoretical result, a scaled up model of the swimming robot is fabricated and characterized in silicone oil using the Buckingham PI theorem for scaling. The results are compared with the theoretically computed values. These robots are intended to swim in stagnation/low velocity biofluid and reach currently inaccessible areas of the human body for disease inspection and possibly treatment. Potential target regions to use these robots include eyeball cavity, cerebrospinal fluid and the urinary system.

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link (url) DOI [BibTex]

link (url) DOI [BibTex]


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Atomic force microscope probe based controlled pushing for nanotribological characterization

Sitti, M.

IEEE/ASME Transactions on mechatronics, 9(2):343-349, IEEE, 2004 (article)

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[BibTex]

[BibTex]

1999


Parameterized modeling and recognition of activities
Parameterized modeling and recognition of activities

Yacoob, Y., Black, M. J.

Computer Vision and Image Understanding, 73(2):232-247, 1999 (article)

Abstract
In this paper we consider a class of human activities—atomic activities—which can be represented as a set of measurements over a finite temporal window (e.g., the motion of human body parts during a walking cycle) and which has a relatively small space of variations in performance. A new approach for modeling and recognition of atomic activities that employs principal component analysis and analytical global transformations is proposed. The modeling of sets of exemplar instances of activities that are similar in duration and involve similar body part motions is achieved by parameterizing their representation using principal component analysis. The recognition of variants of modeled activities is achieved by searching the space of admissible parameterized transformations that these activities can undergo. This formulation iteratively refines the recognition of the class to which the observed activity belongs and the transformation parameters that relate it to the model in its class. We provide several experiments on recognition of articulated and deformable human motions from image motion parameters.

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pdf pdf from publisher DOI [BibTex]

1999


pdf pdf from publisher DOI [BibTex]


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< 研究速報>(< 小特集> マイクロマシン)

Sitti, M., 橋本秀紀,

生産研究, 51(8):651-653, 東京大学, 1999 (article)

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[BibTex]

[BibTex]


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Micro/Nano Manipulation Using Atomic Force Microscope.

Sitti, M., Hashimoto, H.

生産研究, 51(8):651-653, 東京大学生産技術研究所, 1999 (article)

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[BibTex]

[BibTex]


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Virtual Reality-Based Teleoperation in the Micro/Nano World.

Sitti, M., Hashimoto, H.

生産研究, 51(8):654-656, 東京大学生産技術研究所, 1999 (article)

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[BibTex]

[BibTex]


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Teleoperated nano scale object manipulation

Sitti, M., Hashimoto, H.

Recent Advances on Mechatronics, pages: 322-335, Singapore: Springer-Verlag, 1999 (article)

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[BibTex]

[BibTex]