Prof. Dr. Joachim Spatz

Phone:+49 711 689-3611Fax:+ 49 711 689-3612



Latest News

New Paper: A molecular mechanotransduction pathway regulates collective migration of epithelial cells. Das, T., Safferling, K., Rausch, S., Grabe, N., Böhm, H., & Spatz, J. P. (2015). Nature Cell Biology, 17, 276-287. doi:10.1038/ncb3115.

New Paper: Key factors for stable retention of fluorophores and labeled biomolecules in droplet-based microfluidics. Janiesch, J.-W., Weiss, M., Kannenberg, G., Hannabuss, J., Surrey, T., Platzman, I. & Spatz, J. P. (2015). Analytical chemistry, 87(4), 2063-7. doi:10.1021/ac504736e

New Paper: Nanoscale control of surface immobilized BMP-2: toward a quantitative assessment of BMP-mediated signaling events. Schwab, E.H.,  Pohl, T.L.M.,  Haraszti, T., Schwaerzer, G.K., Hiepen, C., Spatz, J.P., Knaus, P. & Cavalcanti-Adam, E.A. (2015). Nano Letters, available online, doi:10.1021/acs.nanolett.5b00315


New Materials and Biosystems (Spatz)

Investigation of the interaction between synthetic and living materials



Biophysics of Cellular Interactions

Synthetic Cell Systems

Cell Signaling and Adhesion

Technical Applications of Biomimetic Nanostructures

Tobacco mosaic virus-based structuring tools

Supramolecular structures and micromechanics

Cell Mechanics and Migration

Single Molecule TIRF Microscopy on Nanostructured Surfaces

Hydrogels and Mechanotransduction

Nanomaterials for Optical and Sensoric Applications

Microfluidics for Synthetic Biology

Bionic Microgenerators and Tunneling Nanotubes (TNTs)

Photoswitchable Biointerphases



The Department explores fundamental and applied research topics in the area of biomaterials, biophysics and biomedicine. Its focus are novel functions and phenomema based on the self-organization of molecules, proteins, nanoparticles, bacteria, and cells as well as their chemical and physical manipulation. In this context we are developing new devices and biomaterial systems (e.g. photoswitchable molecules and proteins, structured interfaces for bio- and optically active interfaces as well as fiber systems for cell matrices) and shedding light on fundamental issues such as individual and collective cell migration, cellular interactions with their environment (cell-cell and cell-matrix adhesion) and, its influence on higher biological functions like immune responses, tissue development and regeneration, wound healing and tumor development. Moreover, the Department addresses issues in synthetic biology, how individual cell functions like cell adhesion and cell migration can be created synthetically. The latter topic is being funded by an ERC Advanced Grant of the EU (together with Benjamin Geiger from the Weizmann Institute of Science), among others.

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