Dr. Ada Cavalcanti-Adam
Head of the CSF Biomaterials and Molecular Biology
Cell adhesion to the extracellular matrix regulates many physiological and pathological events, such as migration, proliferation, differentiation and apoptosis. Upon binding to the extracellular matrix, integrin clustering, cytoplasmic proteins recruitment and actin stress fibers assembly are key processes during adhesion. This results in signaling for active spreading and reorganization of cell architecture.
While it is known that ...