Working Groups

Many mammalian cells are enveloped by a sugar-protein coat. This coat plays a maior role in all interactions of the cell with its environment. Thus our main research interest is the analysis of the dynamic properties of this pericellular matrix.

Biophysics of Cellular Interactions (Heike Böhm)

Many mammalian cells are enveloped by a sugar-protein coat. This coat plays a maior role in all interactions of the cell with its environment. Thus our main research interest is the analysis of the dynamic properties of this pericellular matrix. [more]
The goal of the group is to determine how nanoscale features of the extracellular environment control cell function. We focus on the spatial regulation of integrin receptor clustering and on the cross talk with other transmembrane receptors.

Cell Signaling and Adhesion (Ada Cavalcanti-Adam)

The goal of the group is to determine how nanoscale features of the extracellular environment control cell function. We focus on the spatial regulation of integrin receptor clustering and on the cross talk with other transmembrane receptors. [more]
<span>Collective cell migration is the process of several cells migrating as a cohesive group, in which each individual actively coordinates its own movement with that of its neighbors.</span>

Collective Cell Migration (Tamal Das)

Collective cell migration is the process of several cells migrating as a cohesive group, in which each individual actively coordinates its own movement with that of its neighbors. [more]
Tobacco mosaic virus variants are used as nanoscaffolds for functional molecules such as fluorescent dyes, proteins or peptides. Such modified nanosticks are used as enzyme carriers for the investigation of enzyme complexes or for structuring surfaces and hydrogels supporting cell growth and differentiation.

Tobacco mosaic virus-based structuring tools (Fania Geiger)

Tobacco mosaic virus variants are used as nanoscaffolds for functional molecules such as fluorescent dyes, proteins or peptides. Such modified nanosticks are used as enzyme carriers for the investigation of enzyme complexes or for structuring surfaces and hydrogels supporting cell growth and differentiation. [more]
We are interested in biophysical aspects of dynamic cellular reorganizations, in the development of cell-type specific biomaterials, and in cellular controller systems.

Cell Mechanics and Migration (Ralf Kemkemer)

We are interested in biophysical aspects of dynamic cellular reorganizations, in the development of cell-type specific biomaterials, and in cellular controller systems. [more]
We perform single molecule microscopy based on TIRF excitation to track fluorescent molecules. A major application of this technique is to study the diffusive behaviour of proteins in living cells and their interaction with precisely specified nanostructured surfaces.

Single Molecule TIRF Microscopy on Nanostructured Surfaces (Günter Majer)

We perform single molecule microscopy based on TIRF excitation to track fluorescent molecules. A major application of this technique is to study the diffusive behaviour of proteins in living cells and their interaction with precisely specified nanostructured surfaces. [more]
We are interested in understanding how mammalian cells sense and respond to their mechanical microenvironment.

Hydrogels and Mechanotransduction (Dimitris Missirlis)

We are interested in understanding how mammalian cells sense and respond to their mechanical microenvironment. [more]
Our research is focus on the study of the interaction between cells and the extracellular matrix (ECM) as well as cell-cell interactions with a focus on how these interactions regulate the structure and dynamics of the cell. Understanding the mechanisms underlying these interactions is highly relevant for the investigation of biological processes such as cell survival, proliferation, differentiation, and migration.

Nanoelectronics for Cellular Interfaces (Diego Pallarola)

Our research is focus on the study of the interaction between cells and the extracellular matrix (ECM) as well as cell-cell interactions with a focus on how these interactions regulate the structure and dynamics of the cell. Understanding the mechanisms underlying these interactions is highly relevant for the investigation of biological processes such as cell survival, proliferation, differentiation, and migration. [more]
The major aim of our interdisciplinary research is bridging the gap between the development of droplet-based microfluidic technology and its application in fundamental biological and biomedical research.

Microfluidics for Synthetic Biology (Ilia Platzman)

The major aim of our interdisciplinary research is bridging the gap between the development of droplet-based microfluidic technology and its application in fundamental biological and biomedical research. [more]

AG Friedhelm Serwane

Retina-Organoid-Based Artificial Eye

[more]
In many modern optical appliances unwanted light reflections reduce the image quality notably. Nocturnal moths have solved this problem million of years ago. A nanometre-sized structure on the surface of their eyes results in almost perfect anti-reflective properties. In the nanoAR workgroup we are developing new cost efficient methods to coat commercially available surfaces with a similar, biomimetic nanostructure.

Technical Applications of Biomimetic Nanostructures – nanoAR (Klaus Weishaupt)

In many modern optical appliances unwanted light reflections reduce the image quality notably. Nocturnal moths have solved this problem million of years ago. A nanometre-sized structure on the surface of their eyes results in almost perfect anti-reflective properties. In the nanoAR workgroup we are developing new cost efficient methods to coat commercially available surfaces with a similar, biomimetic nanostructure. [more]
 
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